Biomarkers of gastroenteropancreatic neuroendocrine tumors

被引：0

作者：

d'Herbomez, Michele ^{[1
,2
]}

Coppin, Lucie ^{[2
]}

Bauters, Catherine ^{[3
]}

Carnaille, Bruno ^{[1
,4
]}

Do Cao, Christine ^{[3
]}

机构：

[1] Univ Lille, Fac Med, Villeneuve Dascq, France

[2] CHRU Lille, Dept Biochim, Pole Biol Pathol Genet, Lille, France

[3] CHRU Lille, Clin Endocrinol, Lille, France

[4] CHRU Lille, Serv Chirurg, Endocrinienne, Lille, France

来源：

CORRESPONDANCES EN METABOLISMES HORMONES DIABETES ET NUTRITION | 2016年 / 20卷 / 07期

关键词：

Biomarkers; Gastroenteropancreatic neuro-endocrine tumors; Chromogranin A; Calcitonin; Serotonin; ENETS CONSENSUS GUIDELINES; CHROMOGRANIN-A; NEOPLASMS; UPDATE; MANAGEMENT; CARCINOMAS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neuroendocrine tumors can secrete many specific (proinsulin, gastrin, serotonin, caicitonin) and general biomarkers (chromogranin A, neuron specific enolase). Hormonal evaluation depends of the clinical presentation, the tumor location and their differentiation. CgA in serum is the general biomarker the most performant. One high CgA level must be interpreted with the gastrin concentration and the renal function. The biomarkers are diagnostic, pronostic tools and used for the follow-up. Their interpretation oblige to have specific knowledges.

引用

页码：174 / 177

页数：4

共 15 条

[1] Gastroenteropancreatic endocrine tumors: clinical characterization before therapy [J].

Baudin, Eric .

NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM, 2007, 3 (03) :228-239

[2] Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids [J].

Caplin, M. E. ;

Baudin, E. ;

Ferolla, P. ;

Filosso, P. ;

Garcia-Yuste, M. ;

Lim, E. ;

Oberg, K. ;

Pelosi, G. ;

Perren, A. ;

Rossi, R. E. ;

Travis, W. D. .

ANNALS OF ONCOLOGY, 2015, 26 (08) :1604-1620

[3] Calcitonin: Indications and interpretation [J].

d'Herbomez, Michele .

PRESSE MEDICALE, 2011, 40 (12) :1141-1146

[4] ENETS Consensus Guidelines Update for Gastroduodenal Neuroendocrine Neoplasms [J].

Delle Fave, G. ;

O'Toole, D. ;

Sundin, A. ;

Taal, B. ;

Ferolla, P. ;

Ramage, J. K. ;

Ferone, D. ;

Ito, T. ;

Weber, W. ;

Zheng-Pei, Z. ;

De Herder, W. W. ;

Pascher, A. ;

Ruszniewski, P. .

NEUROENDOCRINOLOGY, 2016, 103 (02) :119-124

[5] ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors [J].

Falconi, M. ;

Eriksson, B. ;

Kaltsas, G. ;

Bartsch, D. K. ;

Capdevila, J. ;

Caplin, M. ;

Kos-Kudla, B. ;

Kwekkeboom, D. ;

Rindi, G. ;

Kloeppel, G. ;

Reed, N. ;

Kianmanesh, R. ;

Jensen, R. T. .

NEUROENDOCRINOLOGY, 2016, 103 (02) :153-171

[6] ENETS Consensus Guidelines for High-Grade Gastroenteropancreatic Neuroendocrine Tumors and Neuroendocrine Carcinomas [J].

Garcia-Carbonero, R. ;

Sorbye, H. ;

Baudin, E. ;

Raymond, E. ;

Wiedenmann, B. ;

Niederle, B. ;

Sedlackova, E. ;

Toumpanakis, C. ;

Anlauf, M. ;

Cwikla, J. B. ;

Caplin, M. ;

O'Toole, D. ;

Perren, A. .

NEUROENDOCRINOLOGY, 2016, 103 (02) :186-194

[7] Multicenter evaluation of a new progastrin-releasing peptide (ProGRP) immunoassay across Europe and China [J].

Korse, Catharina M. ;

Holdenrieder, Stefan ;

Zhi, Xiu-yi ;

Zhang, Xiaotong ;

Qiu, Ling ;

Geistanger, Andrea ;

Lisy, Marcus-Rene ;

Wehnl, Birgit ;

van den Broek, Daan ;

Escudero, Jose M. ;

Standop, Jens ;

Hu, Mu ;

Molina, Rafael .

CLINICA CHIMICA ACTA, 2015, 438 :388-395

[8] The Clinical Relevance of Chromogranin A as a Biomarker for Gastroenteropancreatic Neuroendocrine Tumors [J].

Lawrence, Ben ;

Gustafsson, Bjorn I. ;

Kidd, Mark ;

Pavel, Marianne ;

Svejda, Bernhard ;

Modlin, Irvin M. .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2011, 40 (01) :111-+

[9] A multianalyte PCR blood test outperforms single analyte ELISAs (chromogranin A, pancreastatin, neurokinin A) for neuroendocrine tumor detection [J].

Modlin, Irvin M. ;

Drozdov, Ignat ;

Alaimo, Daniele ;

Callahan, Stephen ;

Teixiera, Nancy ;

Bodei, Lisa ;

Kidd, Mark .

[10] ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum [J].

Niederle, B. ;

Pape, U. -F. ;

Costa, F. ;

Gross, D. ;

Kelestimur, F. ;

Knigge, U. ;

Oberg, K. ;

Pavel, M. ;

Perren, A. ;

Toumpanakis, C. ;

O'Connor, J. ;

O'Toole, D. ;

Krenning, E. ;

Reed, N. ;

Kianmanesh, R. .

NEUROENDOCRINOLOGY, 2016, 103 (02) :125-138

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