The Association Between Psychological Distress and Cancer Mortality in the United States: Results from the 1997-2014 NHIS-NDI Record Linkage Study

被引:23
作者
Lee, Hyunjung [1 ,2 ]
Singh, Gopal K. [3 ]
机构
[1] Hlth Resources & Serv Adm, Off Hlth Equ, Rockville, MD 20852 USA
[2] Oak Ridge Inst Sci & Educ ORISE, Oak Ridge, TN 37830 USA
[3] Hlth Resources & Serv Adm, US Dept Hlth & Human Serv, Off Hlth Equ, Rockville, MD 20857 USA
关键词
Psychological distress; Cancer mortality; NHIS-NDI; Longitudinal; Social determinants; DEPRESSION; ANXIETY; STRESS; DISPARITIES; PROGRESSION; PREDICTOR; OBESITY; WOMEN; RISK; K6;
D O I
10.1093/abm/kaaa111
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Background/Purpose Psychological distress can influence cancer mortality through socioeconomic disadvantage, health-risk behaviors, or reduced access to care. These disadvantages can result in higher risks of cancer occurrence, a delayed cancer diagnosis, hamper adherence to treatment, and provoke inflammatory responses leading to cancer. Previous studies have linked psychological distress to cancer mortality. However, studies are lacking for the U.S. population. Methods This study examines the Kessler six-item psychological distress scale as a risk factor for U.S. cancer mortality using the pooled 1997-2014 data from the National Health Interview Survey (NHIS) linked to National Death Index (NDI) (N = 513,012). Cox proportional hazards regression was used to model survival time as a function of psychological distress and sociodemographic and behavioral covariates. Results In Cox models with 18 years of mortality follow-up, the cancer mortality risk was 80% higher (hazard ratio [HR] = 1.80; 95% CI = 1.64, 1.97) controlling for age; 61% higher (HR = 1.61; 95% CI = 1.46, 1.76) in the SES-adjusted model, and 33% higher (HR = 1.33; 95% CI = 1.21, 1.46) in the fully-adjusted model among adults with serious psychological distress (SPD), compared with adults without psychological distress. Males, non-Hispanic Whites, and adults with incomes at or above 400% of the federal poverty level had greater cancer mortality risk associated with SPD. Using an 8 years of mortality follow-up, those with SPD had 108% increased adjusted risks of mortality from breast cancer. Conclusion Our study findings underscore the significance of addressing psychological well-being in the population as a strategy for reducing cancer mortality.
引用
收藏
页码:621 / 640
页数:20
相关论文
共 59 条
[1]  
[Anonymous], 2018, NATL HLTH INTERVIEW
[2]  
[Anonymous], 2019, CANC PREVENTION EARL
[3]  
[Anonymous], 2019, Major depression
[4]  
[Anonymous], 1991, Event History Analysis
[5]  
[Anonymous], 2018, HLTH US 2017 SPEC FE
[6]   Mortality risk varies according to gender and change in depressive status in very old adults [J].
Anstey, KJ ;
Luszcz, MA .
PSYCHOSOMATIC MEDICINE, 2002, 64 (06) :880-888
[7]   Psychological distress in relation to site specific cancer mortality: pooling of unpublished data from 16 prospective cohort studies [J].
Batty, G. David ;
Russ, Tom C. ;
Stamatakis, Emmanuel ;
Kivimaki, Mika .
BMJ-BRITISH MEDICAL JOURNAL, 2017, 356
[8]  
Blewett LA., 2019, IPUMS HLTH SURVEYS N
[9]   Do stress-related psychosocial factors contribute to cancer incidence and survival? [J].
Chida, Yoichi ;
Hamer, Mark ;
Wardle, Jane ;
Steptoe, Andrew .
NATURE CLINICAL PRACTICE ONCOLOGY, 2008, 5 (08) :466-475
[10]  
Epstein R. M., 2007, PATIENT CTR COMMUNIC