Liquid-Phase Electron Microscopy for Soft Matter Science and Biology

被引：95
|
作者：
Wu, Hanglong [1 ]
Friedrich, Heiner [1 ,2 ]
Patterson, Joseph P. [3 ]
Sommerdijk, Nico A. J. M. [4 ]
de Jonge, Niels [5 ,6 ]
机构：
[1] Eindhoven Univ Technol, Dept Chem Engn & Chem, NL-5600 MB Eindhoven, Netherlands
[2] Eindhoven Univ Technol, Inst Complex Mol Syst, NL-5600 MB Eindhoven, Netherlands
[3] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA
[4] Radboud Univ Nijmegen, Med Ctr, Dept Biochem, NL-6500 HB Nijmegen, Netherlands
[5] INM Leibniz Inst New Mat, D-66123 Saarbrucken, Germany
[6] Saarland Univ, Dept Phys, D-66123 Saarbrucken, Germany
来源：
ADVANCED MATERIALS | 2020年 / 32卷 / 25期
关键词：
beam-sample interactions; dynamic processes; in situ electron microscopy; synthetic materials; IN-SITU; RADIATION-DAMAGE; GOLD NANOPARTICLES; GROWTH-KINETICS; WHOLE CELLS; WET-STEM; RESOLUTION; GRAPHENE; NANOSCALE; CONTRAST;
D O I：
10.1002/adma.202001582
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Innovations in liquid-phase electron microscopy (LP-EM) have made it possible to perform experiments at the optimized conditions needed to examine soft matter. The main obstacle is conducting experiments in such a way that electron beam radiation can be used to obtain answers for scientific questions without changing the structure and (bio)chemical processes in the sample due to the influence of the radiation. By overcoming these experimental difficulties at least partially, LP-EM has evolved into a new microscopy method with nanometer spatial resolution and sub-second temporal resolution for analysis of soft matter in materials science and biology. Both experimental design and applications of LP-EM for soft matter materials science and biological research are reviewed, and a perspective of possible future directions is given.
引用
收藏
页数：21
相关论文
共 50 条
  • [1] Liquid-Phase Electron Microscopy with Controllable Liquid Thickness
    Keskin, Sercan
    Kunnas, Peter
    de Jonge, Niels
    NANO LETTERS, 2019, 19 (07) : 4608 - 4613
  • [2] Liquid-phase Electron Microscopy Imaging of Polymer Dynamics
    Zhang, De-yi
    Li, Jia-ye
    Xu, Zhun
    Wang, Huan
    ACTA POLYMERICA SINICA, 2024, 55 (02): : 235 - 254
  • [3] Preface to the special issue on liquid-phase electron microscopy
    Abellan, Patricia
    de Jonge, Niels
    MICRON, 2019, 119 : 117 - 118
  • [4] Imaging biomacromolecules in action with liquid-phase electron microscopy
    Li, Jia-ye
    Sun, He
    Wang, Huan
    TRENDS IN CHEMISTRY, 2024, 6 (06): : 281 - 284
  • [5] Exploration of Organic Nanomaterials with Liquid-Phase Transmission Electron Microscopy
    Korpanty, Joanna
    Gianneschi, Nathan C.
    ACCOUNTS OF CHEMICAL RESEARCH, 2023, 56 (17) : 2298 - 2312
  • [6] Liquid-phase electron microscopy imaging of cellular and biomolecular systems
    Smith, John W.
    Chen, Qian
    JOURNAL OF MATERIALS CHEMISTRY B, 2020, 8 (37) : 8490 - 8506
  • [7] TRANSMISSION ELECTRON-MICROSCOPY OF LIQUID-PHASE DENSIFIED SIC
    CARPENTER, RW
    BRAUE, W
    CUTLER, RA
    JOURNAL OF MATERIALS RESEARCH, 1991, 6 (09) : 1937 - 1944
  • [8] Electron microscopy of soft matter
    不详
    NATURE MATERIALS, 2003, 2 (04) : 206 - 206
  • [9] Nanoscale Cinematography of Soft Matter System under Liquid-Phase TEM
    Ou, Zihao
    Liu, Chang
    Yao, Lehan
    Chen, Qian
    ACCOUNTS OF MATERIALS RESEARCH, 2020, 1 (01): : 41 - 52
  • [10] Liquid-Phase Transmission Electron Microscopy for Studying Colloidal Inorganic Nanoparticles
    Kim, Byung Hyo
    Yang, Jiwoong
    Lee, Donghoon
    Choi, Back Kyu
    Hyeon, Taeghwan
    Park, Jungwon
    ADVANCED MATERIALS, 2018, 30 (04)
12345