Neuromyelitis optica spectrum disorder mimicking multiple sclerosis

被引：1

作者：

van Rooij, Lucas C. ^{[1
]}

Wattjes, Mike P. ^{[2
]}

de Jong, Brigit A. ^{[3
]}

van Oosten, Bob W. ^{[3
]}

机构：

[1] Haaglanden Med Ctr, Dept Neurol, The Hague, Netherlands

[2] Vrije Univ Amsterdam, Dept Radiol, Med Ctr, Amsterdam, Netherlands

[3] Vrije Univ Amsterdam, Dept Neurol, Med Ctr, Amsterdam, Netherlands

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2017年 / 17卷

关键词：

Neuromyelitis optica spectrum disorder; Multiple sclerosis; Aquaporin; 4; antibodies; Longitudinally extensive transverse myelitis; Rituximab;

D O I：

10.1016/j.msard.2017.06.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: MS is a demyelinating CNS disease and has distinct clinical and radiological features. Neuromyelitis optica spectrum disorder (NMOSD) is an antibody related auto-immune disease known for invalidating episodes of myelitis and optic neuritis. Objective: Reporting the case of a 29-year old woman with a disease course typical for relapsing remitting MS with consistent radiological and spinal fluid findings, who developed longitudinally extensive transverse myelitis (LETM) with positive aquaporin 4 antibodies, fulfilling the diagnostic criteria for NMOSD. Methods: Case report. Results: LETM is not consistent with MS. Consider NMOSD even in patients with typical MS and check for aquaporin-4 antibodies, with important treatment consequences.

引用

页码：54 / 56

页数：3

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