Interim thymus and activation regulated chemokine versus interim 18F-fluorodeoxyglucose positron-emission tomography in classical Hodgkin lymphoma response evaluation

被引：19

作者：

Plattel, Wouter J. ^{[1
]}

Visser, Lydia ^{[2
]}

Diepstra, Arjan ^{[2
]}

Glaudemans, Andor W. J. M. ^{[3
]}

Nijland, Marcel ^{[1
]}

van Meerten, Tom ^{[1
]}

Kluin-Nelemans, Hanneke C. ^{[1
]}

van Imhoff, Gustaaf W. ^{[1
]}

van den Berg, Anke ^{[2
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Hematol, Groningen, Netherlands

[2] Univ Groningen, Univ Med Ctr Groningen, Dept Pathol & Med Biol, Groningen, Netherlands

[3] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2020年 / 190卷 / 01期

关键词：

ADAPTED TREATMENT; PET; ABVD; BIOMARKERS; TRIAL; TARC;

D O I：

10.1111/bjh.16514

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serum thymus and activation regulated chemokine (TARC) levels reflect classical Hodgkin lymphoma (cHL) disease activity and correspond with treatment response. We compared mid-treatment interim TARC (iTARC) with interim F-18-fluorodeoxyglucose positron-emission tomography (iPET) imaging to predict modified progression-free survival (mPFS) in a group of 95 patients with cHL. High iTARC levels were found in nine and positive iPET in 17 patients. The positive predictive value (PPV) of iTARC for a 5-year mPFS event was 88% compared to 47% for iPET. The negative predictive value was comparable at 86% for iTARC and 85% for iPET. Serum iTARC levels more accurately reflect treatment response with a higher PPV compared to iPET.

引用

页码：40 / 44

页数：5

共 15 条

[1] Early Positron Emission Tomography Response-Adapted Treatment in Stage I and II Hodgkin Lymphoma: Final Results of the Randomized EORTC/LYSA/FIL H10 Trial [J].

Andre, Marc P. E. ;

Girinsky, Theodore ;

Federico, Massimo ;

Reman, Oumedaly ;

Fortpied, Catherine ;

Gotti, Manuel ;

Casasnovas, Olivier ;

Brice, Pauline ;

van der Maazen, Richard ;

Re, Alessandro ;

Edeline, Veronique ;

Ferme, Christophe ;

van Imhoff, Gustaaf ;

Merli, Francesco ;

Bouabdallah, Reda ;

Sebban, Catherine ;

Specht, Lena ;

Stamatoullas, Aspasia ;

Delarue, Richard ;

Fiaccadori, Valeria ;

Bellei, Monica ;

Raveloarivahy, Tiana ;

Versari, Annibale ;

Hutchings, Martin ;

Meignan, Michel ;

Raemaekers, John .

JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (16) :1786-+

[2] International Validation Study for Interim PET in ABVD-Treated, Advanced-Stage Hodgkin Lymphoma: Interpretation Criteria and Concordance Rate Among Reviewers [J].

Biggi, Alberto ;

Gallamini, Andrea ;

Chauvie, Stephane ;

Hutchings, Martin ;

Kostakoglu, Lale ;

Gregianin, Michele ;

Meignan, Michel ;

Malkowski, Bogdan ;

Hofman, Michael S. ;

Barrington, Sally F. .

JOURNAL OF NUCLEAR MEDICINE, 2013, 54 (05) :683-690

[3] PET-guided treatment in patients with advanced-stage Hodgkin's lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin Study Group [J].

Borchmann, Peter ;

Goergen, Helen ;

Kobe, Carsten ;

Lohri, Andreas ;

Greil, Richard ;

Eichenauer, Dennis A. ;

Zijlstra, Josee M. ;

Markova, Jana ;

Meissner, Julia ;

Feuring-Buske, Michaela ;

Huttmann, Andreas ;

Dierlamm, Judith ;

Soekler, Martin ;

Beck, Hans-Joachim ;

Willenbacher, Wolfgang ;

Ludwig, Wolf-Dieter ;

Pabst, Thomas ;

Topp, Max S. ;

Hitz, Felicitas ;

Bentz, Martin ;

Keller, Ulrich Bernd ;

Kuhnhardt, Dagmar ;

Ostermann, Helmut ;

Schmitz, Norbert ;

Hertenstein, Bernd ;

Aulitzky, Walter ;

Maschmeyer, Georg ;

Vieler, Tom ;

Eich, Hans ;

Baues, Christian ;

Stein, Harald ;

Fuchs, Michael ;

Kuhnert, Georg ;

Diehl, Volker ;

Dietlein, Markus ;

Engert, Andreas .

LANCET, 2017, 390 (10114) :2790-2802

[4] Eight Cycles of ABVD Versus Four Cycles of BEACOPPescalated Plus Four Cycles of BEACOPPbaseline in Stage III to IV, International Prognostic Score ≥ 3, High-Risk Hodgkin Lymphoma: First Results of the Phase III EORTC 20012 Intergroup Trial [J].

Carde, Patrice ;

Karrasch, Matthias ;

Fortpied, Catherine ;

Brice, Pauline ;

Khaled, Hussein ;

Casasnovas, Olivier ;

Caillot, Denis ;

Gaillard, Isabelle ;

Bologna, Serge ;

Ferme, Christophe ;

Lugtenburg, Pieternella Johanna ;

Morschhauser, Frank ;

Aurer, Igor ;

Coiffier, Bertrand ;

Meyer, Ralph ;

Seftel, Matthew ;

Wolf, Max ;

Glimelius, Bengt ;

Sureda, Anna ;

Mounier, Nicolas .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (17) :2028-+

[5] Recommendations for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The Lugano Classification [J].

Cheson, Bruce D. ;

Fisher, Richard I. ;

Barrington, Sally F. ;

Cavalli, Franco ;

Schwartz, Lawrence H. ;

Zucca, Emanuele ;

Lister, T. Andrew .

JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (27) :3059-+

[6] Early reduction of serum TARC levels may predict for success of ABVD as frontline treatment in patients with Hodgkin Lymphoma [J].

Guidetti, A. ;

Mazzocchi, A. ;

Miceli, R. ;

Paterno, E. ;

Taverna, F. ;

Spina, F. ;

Crippa, F. ;

Farina, L. ;

Corradini, P. ;

Gianni, A. M. ;

Viviani, S. .

LEUKEMIA RESEARCH, 2017, 62 :91-97

[7] Serum levels of TARC, MDC, IL-10, and soluble CD163 in Hodgkin lymphoma: a SWOG S0816 correlative study [J].

Hsi, Eric D. ;

Li, Hongli ;

Nixon, Andrew B. ;

Schoder, Heiko ;

Bartlett, Nancy L. ;

LeBlanc, Michael ;

Smith, Sonali ;

Kahl, Brad S. ;

Leonard, John P. ;

Evens, Andrew M. ;

Scott, David W. ;

Rimsza, Lisa M. ;

Friedberg, Jonathan W. .

BLOOD, 2019, 133 (16) :1762-1765

[8] In Vivo Treatment Sensitivity Testing With Positron Emission Tomography/Computed Tomography After One Cycle of Chemotherapy for Hodgkin Lymphoma [J].

Hutchings, Martin ;

Kostakoglu, Lale ;

Zaucha, Jan Maciej ;

Malkowski, Bogdan ;

Biggi, Alberto ;

Danielewicz, Iwona ;

Loft, Annika ;

Specht, Lena ;

Lamonica, Dominick ;

Czuczman, Myron S. ;

Nanni, Christina ;

Zinzani, Pier Luigi ;

Diehl, Louis ;

Stern, Richard ;

Coleman, Morton .

JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (25) :2705-+

[9] Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin's Lymphoma [J].

Johnson, Peter ;

Federico, Massimo ;

Kirkwood, Amy ;

Fossa, Alexander ;

Berkahn, Leanne ;

Carella, Angelo ;

d'Amore, Francesco ;

Enblad, Gunilla ;

Franceschetto, Antonella ;

Fulham, Michael ;

Luminari, Stefano ;

O'Doherty, Michael ;

Patrick, Pip ;

Roberts, Thomas ;

Sidra, Gamal ;

Stevens, Lindsey ;

Smith, Paul ;

Trotman, Judith ;

Viney, Zaid ;

Radford, John ;

Barrington, Sally .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 374 (25) :2419-2429

[10] Serum chemokine levels in Hodgkin lymphoma patients: highly increased levels of CCL17 and CCL22 [J].

Niens, Marijke ;

Visser, Lydia ;

Nolte, Ilja M. ;

van der Steege, Gerrit ;

Diepstra, Arjan ;

Cordano, Pablo ;

Jarrett, Ruth F. ;

te Meerman, Gerard J. ;

Poppema, Sibrand ;

van den Berg, Anke .

BRITISH JOURNAL OF HAEMATOLOGY, 2008, 140 (05) :527-536

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