Effect of Laparoscopic Roux-en-Y Gastroenterostomy with BMI < 35 kg/m2 in Type 2 Diabetes Mellitus

被引：26
作者：
Zhu, Liyong [1 ]
Mo, Zhaohui [2 ]
Yang, Xiangwu [1 ]
Liu, Shengping [1 ]
Wang, Guohui [1 ]
Li, Pengzhou [1 ]
Tan, Juan [1 ]
Ye, Fei [1 ]
Strain, Jeff [3 ]
Im, Ibrahim [3 ]
Zhu, Shaihong [1 ]
机构：
[1] Cent South Univ, Dept Gen Surg, Xiangya Hosp 3, Changsha 410013, Hunan, Peoples R China
[2] Cent South Univ, Dept Endocrinol, Xiangya Hosp 3, Changsha 410013, Hunan, Peoples R China
[3] Englewood Hosp & Med Ctr, Dept Surg, Englewood, NJ 07631 USA
来源：
OBESITY SURGERY | 2012年 / 22卷 / 10期
关键词：
Type 2 diabetes mellitus; Laparoscopic Roux-en-Y gastroenterostomy; GASTRIC BYPASS-SURGERY; WEIGHT-LOSS; OBESITY; IMPROVEMENT; PREVALENCE; OPERATION; DISEASE;
D O I：
10.1007/s11695-012-0694-0
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Roux-en-Y gastric bypass (RGB) has been endorsed by the "First World Congress on International Therapies for Type 2 diabetes" as a possible therapeutic option in patients with type 2 diabetes with a body mass index (BMI) of less than 35 kg/m(2). In the present study, we assessed the improvement in clinical indicators associated with laparoscopic Roux-en-Y gastric bypass (LRYGB) in patients with non-obese type 2 diabetes mellitus (T2DM). LRYGB was performed in 30 T2DM patients with a BMI < 35 kg/m(2). The patients were followed up for 1 year. Pre- and postoperative changes in BMI, waist circumference, and biochemical indicators including fasting plasma glucose and glycosylated hemoglobin were recorded. Significant reduction in glycosylated hemoglobin from 8.02 +/- 1.77 to 5.59 +/- 1.02 % (p < 0.05) at 12 months was noted. Diabetes was completely resolved in nine cases, resulting in discontinuation of diabetes-related medication. No significant surgical complications occurred. LRYGB is beneficial for non-obese T2DM patients in China.
引用
收藏
页码：1562 / 1567
页数：6
相关论文
共 25 条
  • [1] ALBERTI KGM, 1999, DEFINITION DIAGNOS 1
  • [2] Improvement and stabilization of chronic kidney disease after gastric bypass
    Alexander, J. Wesley
    Goodman, Hope R.
    Hawver, Lisa R. Martin
    Cardi, Michael A.
    [J]. SURGERY FOR OBESITY AND RELATED DISEASES, 2009, 5 (02) : 237 - 241
  • [3] Do Incretins Play a Role in the Remission of Type 2 Diabetes after Gastric Bypass Surgery: What are the Evidence?
    Bose, Mousumi
    Olivan, Blanca
    Teixeira, Julio
    Pi-Sunyer, F. Xavier
    Laferrere, Blandine
    [J]. OBESITY SURGERY, 2009, 19 (02) : 217 - 229
  • [4] Bariatric surgery: A systematic review and meta-analysis
    Buchwald, H
    Avidor, Y
    Braunwald, E
    Jensen, MD
    Pories, W
    Fahrbach, K
    Schoelles, K
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (14): : 1724 - 1737
  • [5] Duodenal-jejunal bypass for the treatment of type 2 diabetes in patients with body mass index of 22-34 kg/m2: a report of 2 cases
    Cohen, Ricardo V.
    Schiavon, Carlos A.
    Pinheiro, Jose S.
    Correa, Jose Luiz
    Rubino, Francesco
    [J]. SURGERY FOR OBESITY AND RELATED DISEASES, 2007, 3 (02) : 195 - 197
  • [6] Gastric bypass for obesity: Mechanisms of weight loss and diabetes resolution
    Cummings, DE
    Overduin, J
    Foster-Schubert, KE
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (06) : 2608 - 2615
  • [7] Results of 281 consecutive total laparoscopic Roux-en-Y gastric bypasses to treat morbid obesity
    DeMaria, J
    Sugerman, HJ
    Kellum, JM
    Meador, JG
    Wolfe, LG
    [J]. ANNALS OF SURGERY, 2002, 235 (05) : 640 - 645
  • [8] Laparoscopic ileal interposition associated to a diverted sleeve gastrectomy is an effective operation for the treatment of type 2 diabetes mellitus patients with BMI 21-29
    DePaula, A. L.
    Macedo, A. L. V.
    Mota, B. R.
    Schraibman, V.
    [J]. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2009, 23 (06): : 1313 - 1320
  • [9] Upper Gastrointestinal Symptoms and Associated Disorders in Morbidly Obese Patients: A Prospective Study
    Dutta, Sudhir K.
    Arora, Manish
    Kireet, Agrawal
    Bashandy, Hany
    Gandsas, Alejandro
    [J]. DIGESTIVE DISEASES AND SCIENCES, 2009, 54 (06) : 1243 - 1246
  • [10] Clinical Improvement After Duodenojejunal Bypass for Nonobese Type 2 Diabetes Despite Minimal Improvement in Glycemic Homeostasis
    Ferzli, G. S.
    Dominique, E.
    Ciaglia, M.
    Bluth, M. H.
    Gonzalez, A.
    Fingerhut, A.
    [J]. WORLD JOURNAL OF SURGERY, 2009, 33 (05) : 972 - 979
123