Ethnic differences in the distribution of interleukin-6 polymorphisms among three Brazilian ethnic groups

被引：10
作者：
Gadelha, SR
Alcantara, LC
Costa, GCS
Rios, DL
Galvao-Castro, B
机构：
[1] Fundacao Oswaldo Cruz, Lab Avancado Saude Publ, Ctr Pesquisas Goncalo Moniz, Salvador, BA, Brazil
[2] Escola Bahiana Med & Saude Publ, Fdn Bahiana Desenvolvimento Ciencias, Salvador, BA, Brazil
来源：
HUMAN BIOLOGY | 2005年 / 77卷 / 04期
关键词：
interleukin-6; IL-6; gene; polymorphisms; Brazilian populations;
D O I：
10.1353/hub.2005.0061
中图分类号：
Q98 [人类学];
学科分类号：
030303 ;
摘要：
Polymorphisms in the interleukin-6 promoter region have been associated with diseases. In this study we investigated the -634G/C and -174G/C IL-6 promoter polymorphisms in three Brazilian ethnic groups. We verified that the allele frequencies of the two polymorphisms and haplotype frequencies varied significantly between the populations.
引用
收藏
页码：509 / 514
页数：6
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