Effects of a Combination of Water-Soluble Coenzyme Q10 and Collagen on Skin Parameters and Condition: Results of a Randomised, Placebo-Controlled, Double-Blind Study

被引:21
作者
Zmitek, Katja [1 ,2 ]
Zmitek, Janko [1 ]
Butina, Mirjam Rogl [1 ,3 ]
Pogacnik, Tina [1 ]
机构
[1] VIST Higher Sch Appl Sci, Inst Cosmet, Gerbiceva Ul 51A, SI-1000 Ljubljana, Slovenia
[2] Nutr Inst, Trzaska Cesta 40, SI-1000 Ljubljana, Slovenia
[3] Dermatol Rogl Fabjan, Derceva Ul 35, SI-1000 Ljubljana, Slovenia
关键词
Coenzyme Q10; Q10Vital; CoQ10; collagen peptides; skin health; dermis density; PEPTIDES; SUPPLEMENTATION; MATRIX; ANTIOXIDANTS; MOISTURE; COQ(10); HEALTH; WOMEN; Q(10); SIGNS;
D O I
10.3390/nu12030618
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Skin is a complex and dynamic organ that provides a protective interface between the external environment and the body; changes in skin appearance are often the first visible signs of aging. It is well established that nutrients and other bioactive substances have important roles in the structure and functions of human skin; however, the effects of dietary supplementation of such bioactives are much less investigated. The objective of this randomised, double-blind placebo-controlled study was to investigate the effects of liquid food supplement, characterised by a combination of water-soluble coenzyme Q10 (Q10Vital (R)) and collagen, on dermal density and other skin parameters in comparison to placebo. The trial was performed on 34 healthy women aged 40-65 that received either the test product (n = 17) or the placebo (n = 17) for twelve weeks. Measurements and assessments of skin parameters were performed at baseline and after 12 weeks of intervention. We observed improved dermis density, reduced periorbital wrinkle area and the total wrinkle score, and improved skin smoothness. On the other hand, changes in skin hydration, dermis thickness, transepidermal water loss (TEWL) and viscoelasticity were not significant.
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页数:13
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