Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany

被引:9
作者
Dziodzio, Tomasz [1 ,2 ]
Hillebrandt, Karl Herbert [1 ,2 ]
Knitter, Sebastian [1 ]
Noesser, Maximilian [1 ]
Globke, Brigitta [1 ]
Ritschl, Paul Viktor [1 ,2 ]
Biebl, Matthias [1 ]
Denecke, Christian [1 ]
Raakow, Jonas [1 ]
Lurje, Georg [1 ]
Schoening, Wenzel [1 ]
Schmelzle, Moritz [1 ]
Kahl, Andreas [3 ]
Futterer, Markus [4 ]
Budde, Klemens [3 ]
Eckardt, Kai-Uwe [3 ]
Halleck, Fabian [3 ]
Pratschke, Johann [1 ]
Oellinger, Robert [1 ]
机构
[1] Charite Univ Med Berlin, Dept Surg, Campus Charite Mitte, Campus Virchow Klinikum, Augustenburger Pl 1, D-13352 Berlin, Germany
[2] Berlin Inst Hlth BIH, BIH Charite Clinician Scientist Program, Berlin, Germany
[3] Charite Univ Med Berlin, Dept Nephrol & Med Intens Care, Berlin, Germany
[4] Charite Univ Med Berlin, Dept Endocrinol & Metab Dis, Berlin, Germany
关键词
Obesity; End-stage renal disease; Kidney transplantation; Bariatric surgery; OBESITY; RISK; CANDIDATES; OUTCOMES; DISEASE;
D O I
10.1007/s11695-022-06000-4
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background Obesity in the recipient is linked to inferior transplant outcome. Consequently, access to kidney transplantation (KT) is often restricted by body mass index (BMI) thresholds. Bariatric surgery (BS) has been established as a superior treatment for obesity compared to conservative measures, but it is unclear whether it is beneficial for patients on the waiting list. Methods A national survey consisting of 16 questions was sent to all heads of German KT centers. Current situation of KT candidates with obesity and the status of BS were queried. Results Center response rate was 100%. Obesity in KT candidates was considered an important issue (96.1%; n = 49/51) and 68.6% (n = 35/51) of departments responded to use absolute BMI thresholds for KT waiting list access with >= 35 kg/m(2) (45.1%; n = 23/51) as the most common threshold. BS was considered an appropriate weight loss therapy (92.2%; n = 47/51), in particular before KT (88.2%; n = 45/51). Sleeve gastrectomy was the most favored procedure (77.1%; n = 37/51). Twenty-one (41.2%) departments responded to evaluate KT candidates with obesity by default but only 11 (21.6%) had experience with >= n = 5 transplants after BS. Concerns against BS were malabsorption of immunosuppressive therapy (39.2%; n = 20/51), perioperative morbidity (17.6%; n = 9/51), and malnutrition (13.7%; n = 7/51). Conclusions Obesity is potentially limiting access for KT. Despite commonly used BMI limits, only few German centers consider BS for obesity treatment in KT candidates by default. A national multicenter study is desired by nearly all heads of German transplant centers to prospectively assess the potentials, risks, and safety of BS in KT waitlisted patients.
引用
收藏
页码:1641 / 1648
页数:8
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