Validation of the GRACE Risk Score for Hospital Mortality in Patients With Acute Coronary Syndrome in the Arab Middle East

被引：21

作者：

Yusufali, Afzalhussein ^{[1
]}

Zubaid, Mohammad ^{[2
]}

Al-Zakwani, Ibrahim ^{[3
,4
]}

Alsheikh-Ali, Alawi A. ^{[5
,10
]}

Al-Mallah, Mouaz H. ^{[6
,7
]}

Al Suwaidi, Jassim ^{[8
,9
]}

AlMahmeed, Wael ^{[10
]}

Rashed, Wafa ^{[11
]}

Sulaiman, Kadhim ^{[12
]}

Amin, Haitham ^{[13
]}

机构：

[1] Dubai Hlth Author, Dubai Heart Ctr, Dubai, U Arab Emirates

[2] Kuwait Univ, Fac Med, Dept Med, Kuwait, Kuwait

[3] Sultan Qaboos Univ, Dept Pharmacol & Clin Pharm, Coll Med & Hlth Sci, Muscat, Oman

[4] Gulf Hlth Res, Muscat, Oman

[5] Tufts Univ, Sch Med, Inst Clin Res & Hlth Policy Studies, Boston, MA 02111 USA

[6] Wayne State Univ, Detroit, MI USA

[7] Henry Ford Hosp, Detroit, MI 48202 USA

[8] Hamad Gen Hosp, Doha, Qatar

[9] Hamad Med Corp, Doha, Qatar

[10] Sheikh Khalifa Med City, Abu Dhabi, U Arab Emirates

[11] Mubarak Al Kabeer Hosp, Minist Hlth, Dept Med, Kuwait, Kuwait

[12] Royal Hosp, Muscat, Oman

[13] Mohammed Bin Khalifa Cardiac Ctr, Manama, Bahrain

来源：

ANGIOLOGY | 2011年 / 62卷 / 05期

关键词：

acute coronary syndrome; risk scores; risk stratification; prognosis; EVENTS GULF RACE; MYOCARDIAL-INFARCTION; GLOBAL REGISTRY; POSTDISCHARGE DEATH; PREDICTION MODEL; TASK-FORCE; MANAGEMENT; OUTCOMES; STRATIFICATION; CARDIOLOGY;

D O I：

10.1177/0003319710387921

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Our objective was to validate the Global Registry of Acute Coronary Events (GRACE) risk score for in-hospital mortality in a Middle Eastern acute coronary syndrome (ACS) population enrolled in the Gulf Registry of Acute Coronary Events (Gulf RACE). Out of 8176, unselected, consecutive patients with ACS, during 6 months in 2006 and 2007 from 63 hospitals in 6 Arab countries in the Middle East Gulf region, 7709 (94.3%) with available data were included. The main outcome measures were discriminatory performance (using C-index) and calibration of the GRACE risk score (in-hospital mortality predicted by GRACE risk score versus the actual mortality). In-hospital mortality in the Gulf RACE was 3.09% (n = 238). The discriminatory performance of the GRACE risk scores in the Gulf RACE was good overall (C-index = 0.86). Observed and predicted risk corresponded well in each stratum of risk of in-hospital mortality. This suggests its suitability for clinical use in this patient population.

引用

页码：390 / 396

页数：7

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