Transfusion-related acute lung injury prevention measures and their impact at Canadian Blood Services

被引:72
作者
Lin, Yulia
Saw, Chee-Loong
Hannach, Barbara
Goldman, Mindy [1 ]
机构
[1] Canadian Blood Serv, Ottawa, ON K1G 4J5, Canada
关键词
PLASMA; REDUCTION; RISK; POLICIES; TRALI;
D O I
10.1111/j.1537-2995.2011.03330.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: Blood operators have taken measures to reduce transfusion-related acute lung injury (TRALI). We classified suspected TRALI cases reported to Canadian Blood Services from 2001 to 2009 and assessed the impact of TRALI reduction measures. STUDY DESIGN AND METHODS: Using Canadian Consensus Conference definitions, cases were reviewed by two experts or, from 2006 to 2009, a TRALI Medical Review Group (TMRG). Detection of HLA antibodies was performed using the Luminex system starting in 2008. Measures implemented from 2007 to 2009 included use of predominantly male plasma, suspension of buffy coat platelets in male plasma, and deferral of females with a pregnancy history from plateletpheresis. The buffy coat production method was implemented from 2005 to 2008. RESULTS: Reporting of all suspected TRALI cases, as well as cases classified as definite or possible, increased from 2001 to 2004, was stable from 2004 to 2007, and declined in 2008 to 2009. The decline was most marked for plasma-associated cases, but occurred for all components. TMRG consensus on classification was achieved in 56% of cases. Cases identified as definitive or possible TRALI were significantly more likely to have donor antibody against a corresponding recipient antigen, compared to other cases. CONCLUSION: Hemovigilance data demonstrated an initial increase in TRALI cases, likely due to increased adverse event reporting and awareness of TRALI, followed by a decrease in cases related to all components. TRALI prevention measures and possibly the switch to the buffy coat production method may have contributed to the decline. Classification of cases remains challenging.
引用
收藏
页码:567 / 574
页数:8
相关论文
共 27 条
[1]  
[Anonymous], FAT REP FDA FOLL BLO
[2]   The pathogenesis of transfusion-related acute lung injury (TRALI) [J].
Bux, Jurgen ;
Sachs, Ulrich J. H. .
BRITISH JOURNAL OF HAEMATOLOGY, 2007, 136 (06) :788-799
[3]   Ten years of hemovigilance reports of transfusion-related acute lung injury in the United Kingdom and the impact of preferential use of male donor plasma [J].
Chapman, Catherine E. ;
Stainsby, Dorothy ;
Jones, Hilary ;
Love, Elizabeth ;
Massey, Edwin ;
Win, Nay ;
Navarrete, Cristina ;
Lucas, Geoff ;
Soni, Neil ;
Morgan, Cliff ;
Choo, Louise ;
Cohen, Hannah ;
Williamson, Lorna M. .
TRANSFUSION, 2009, 49 (03) :440-452
[4]   Effective reduction of transfusion-related acute lung injury risk with male-predominant plasma strategy in the American Red Cross (2006-2008) [J].
Eder, Anne F. ;
Herron, Ross M., Jr. ;
Strupp, Annie ;
Dy, Beth ;
White, Jenni ;
Notari, Edward P. ;
Dodd, Roger Y. ;
Benjamin, Richard J. .
TRANSFUSION, 2010, 50 (08) :1732-1742
[5]   Measures to prevent TRALI [J].
Engelfriet, C. P. ;
Reesink, H. W. ;
Wendel, S. ;
Biagini, S. ;
Trigo, F. ;
Fontao-Wendel, R. ;
Taaning, E. ;
Jorgensen, J. ;
Riisom, K. ;
Krusius, T. ;
Koskinen, S. ;
Kretschmer, V. ;
Karger, R. ;
Lawlor, E. ;
Okazaki, H. ;
Charlewood, R. ;
Brand, A. ;
Solheim, B. G. ;
Flesland, O. ;
Letowska, M. ;
Zupanska, B. ;
Muniz-Diaz, E. ;
Senn, M. ;
Mansourri-Taleghani, B. ;
Chapman, C. E. ;
Massey, E. ;
Navarrete, C. ;
Win, N. ;
Williamson, L. M. ;
Stainsby, D. ;
Kleinman, S. ;
Kopko, P. M. ;
Silva, M. ;
Shulman, I. ;
Hollness, L. .
VOX SANGUINIS, 2007, 92 (03) :258-277
[6]  
FDA/Center for Biologics Evaluation and Research Office of Compliance and Biologics Quality Division of Inspections and Surveillance, 2009, FAT REP FDA FOLL BLO
[7]   Transfusion-related acute lung injury in the critically III: Prospective nested case-control study [J].
Gajic, Ognjen ;
Rana, Rimki ;
Winters, Jeffrey L. ;
Yilmaz, Murat ;
Mendez, Lose L. ;
Rickman, Otis B. ;
O'Byrne, Megan M. ;
Evenson, Laura K. ;
Malinchoc, Michael ;
DeGoey, Steven R. ;
Afessa, Bekele ;
Hubmayr, Rolf D. ;
Moore, S. Breanndan .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 176 (09) :886-891
[8]   Proceedings of a consensus conference: Towards an understanding of TRALI [J].
Goldman, M ;
Webert, KE ;
Arnold, DM ;
Freedman, J ;
Hannon, J ;
Blajchman, MA .
TRANSFUSION MEDICINE REVIEWS, 2005, 19 (01) :2-31
[9]   Toward an understanding of transfusion-related acute lung injury: statement of a consensus panel [J].
Kleinman, S ;
Caulfield, T ;
Chan, P ;
Davenport, R ;
McFarland, I ;
McPhedran, S ;
Meade, M ;
Morrison, D ;
Pinsent, T ;
Robillard, P ;
Slinger, P .
TRANSFUSION, 2004, 44 (12) :1774-1789
[10]   A national survey of transfusion-related acute lung injury risk reduction policies for platelets and plasma in the United States [J].
Kleinman, Steven ;
Grossman, Brenda ;
Kopko, Patricia .
TRANSFUSION, 2010, 50 (06) :1312-1321