Quantification of Clostridium difficile in Antibiotic-Associated-Diarrhea Patients

被引：30

作者：

Naaber, Paul ^{[1
,2
]}

Stsepetova, Jelena ^{[2
]}

Smidt, Imbi ^{[2
]}

Raetsep, Merle ^{[2
]}

Koljalg, Siiri ^{[2
,3
]}

Loivukene, Krista ^{[3
]}

Jaanimaee, Liis ^{[2
]}

Lohr, Iren H. ^{[1
]}

Natas, Olav B. ^{[1
]}

Truusalu, Kai ^{[2
]}

Sepp, Epp ^{[2
]}

机构：

[1] Stavanger Univ Hosp, Dept Med Microbiol, N-4068 Stavanger, Norway

[2] Univ Tartu, Dept Microbiol, EE-50411 Tartu, Estonia

[3] Tartu Univ Hosp, Dept Clin Microbiol, EE-50406 Tartu, Estonia

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 10期

关键词：

REAL-TIME PCR; FECAL LACTOFERRIN; DISEASE; LEUKOCYTES; MICROBIOTA; COLITIS; SAMPLES; ASSAY;

D O I：

10.1128/JCM.05115-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Comparing culture- and non-culture-based methods for quantifying Clostridium difficile in antibiotic-associated- diarrhea patients, we found that the real-time PCR method correlated well with quantitative culture and was more sensitive. A positive association between the population levels of C. difficile and the presence of its toxins was found.

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收藏

页码：3656 / 3658

页数：3

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