Ingenane diterpenoids from Euphorbia esula

被引:38
作者
Lu, Zhi-Qiang [1 ]
Yang, Min [1 ]
Zhang, Jin-Qiang [1 ]
Chen, Guang-Tong [1 ]
Huang, Hui-Lian [1 ]
Guan, Shu-Hong [1 ]
Ma, Chao [1 ]
Liu, Xuan [1 ]
Guo, De-An [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China
关键词
Euphorbia esula; Euphorbiaceae; diterpenoids; ingenane;
D O I
10.1016/j.phytochem.2007.09.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An extensive study of metabolites present in Euphorbia esula led to isolation of 16 ingenane diterpenoids 1-16 together with the known ingenane derivative 17 and four known cycloartane triterpenoids. Their structures were elucidated on the basis of spectroscopic studies and comparison with known related compounds. All the compounds were assayed for their inhibitory activity against human HeLa cervical cancer cell line. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:812 / 819
页数:8
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