On the relation between initial value and slope

被引：13

作者：

Byth, K

Cox, DR

机构：

[1] Univ Sydney, Clin Trials Ctr, NHMRC, Camperdown, NSW 1450, Australia

[2] Westmead Hosp, Westmead Millenium Inst, Westmead, NSW 2145, Australia

来源：

BIOSTATISTICS | 2005年 / 6卷 / 03期

关键词：

Huntington's disease; initial value; longitudinal data; regression model with random coefficients; regression to the mean; slope;

D O I：

10.1093/biostatistics/kxi017

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Suppose measurements of a particular feature are collected at baseline and at a number of subsequent time points and that for each individual there is a roughly linear trend in time. This paper takes three approaches to testing whether there is a relation between the initial value and the slope. It also considers whether the initial value for an individual is a useful predictor of the slope for that individual. The problems are formulated in terms of regression models with random coefficients. The solutions are illustrated using data from an observational study of clinical correlates of disability and progression in Huntington's disease.

引用

页码：395 / 403

页数：9

共 11 条

[1]

Burton P, 1998, STAT MED, V17, P1261, DOI 10.1002/(SICI)1097-0258(19980615)17:11<1261::AID-SIM846>3.0.CO

[2]

2-Z

[3]

Galton F., 1869, HEREDITARY GENIUS

[4] Unified Huntington's disease rating scale: Reliability and consistency [J].

Kieburtz, K ;

Penney, JB ;

Como, P ;

Ranen, N ;

Shoulson, I ;

Feigin, A ;

Abwender, D ;

Greenamyre, JT ;

Higgins, D ;

Marshall, FJ ;

Goldstein, J ;

Steinberg, K ;

Shih, C ;

Richard, I ;

Hickey, C ;

Zimmerman, C ;

Orme, C ;

Claude, K ;

Oakes, D ;

Sax, DS ;

Kim, A ;

Hersch, S ;

Jones, R ;

Auchus, A ;

Olsen, D ;

BisseyBlack, C ;

Rubin, A ;

Schwartz, R ;

Dubinsky, R ;

Mallonee, W ;

Gray, C ;

Godfrey, N ;

Suter, G ;

Shannon, KM ;

Stebbins, GT ;

Jaglin, JA ;

Marder, K ;

Taylor, S ;

Louis, E ;

Moskowitz, C ;

Thorne, D ;

Zubin, N ;

Wexler, N ;

Swenson, MR ;

Paulsen, J ;

Swerdlow, N ;

Albin, R ;

Wernette, C ;

Walker, F ;

Hunt, V .

MOVEMENT DISORDERS, 1996, 11 (02) :136-142

[5] RANDOM-EFFECTS MODELS FOR LONGITUDINAL DATA [J].

LAIRD, NM ;

WARE, JH .

BIOMETRICS, 1982, 38 (04) :963-974

[6]

Leyland AH, 2001, MULTILEVEL MODELLING

[7] Huntington's disease - Clinical correlates of disability and progression [J].

Mahant, N ;

McCusker, EA ;

Byth, K ;

Graham, S .

NEUROLOGY, 2003, 61 (08) :1085-1092

[8]

Molenberghs Geert., 2000, Linear Mixed Models for Longitudinal Data

[9]

Omar RZ, 1999, STAT MED, V18, P1587, DOI 10.1002/(SICI)1097-0258(19990715)18:13<1587::AID-SIM141>3.0.CO

[10]

2-Z

← 1 2 →