Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson's disease

被引:75
作者
Smolensky, Luba [1 ]
Amondikar, Ninad [1 ]
Crawford, Karen [2 ]
Neu, Scott [2 ]
Kopil, Catherine M. [1 ]
Daeschler, Margaret [1 ]
Riley, Lindsey [1 ]
Brown, Ethan [3 ]
Toga, Arthur W. [2 ]
Tanner, Caroline [3 ]
机构
[1] Michael J Fox Fdn Parkinsons Dis Res, Res Partnerships, 111 W 33rd St, New York, NY 10019 USA
[2] Univ Southern Calif, Lab Neuro Imaging, Mark & Mary Stevens Neuroimaging & Informat Inst, Ken Sch Med USC, 2025 Zonal Ave, Los Angeles, CA 90033 USA
[3] Univ Calif San Francisco, Sch Med, 1635 Divsadero St, San Francisco, CA 94115 USA
关键词
D O I
10.1038/s41597-020-0401-2
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Measurement(s)Parkinson's disease center dot Patient Reported Outcome center dot SNPTechnology Type(s)questionnaire center dot crowd sourced data generation center dot single-nucleotide polymorphism analysisFactor Type(s)cohort center dot data acquisition source center dot temporal interval center dot environmental risk factor center dot mds updrs center dot geriatric depression scale center dot medical history center dot family neurological history center dot sleep disorder center dot handedness center dot demographics center dot physical activities center dot caregiver center dot daily living center dot LRRK2 center dot APOE center dot SNCA center dot GBASample Characteristic - OrganismHomo sapiens Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.11794011 Fox Insight is an online, longitudinal health study of people with and without Parkinson's disease with targeted enrollment set to at least 125,000 individuals. Fox Insight data is a rich data set facilitating discovery, validation, and reproducibility in Parkinson's disease research. The dataset is generated through routine longitudinal assessments (health and medical questionnaires evaluated at regular cycles), one-time questionnaires about environmental exposure and healthcare preferences, and genetic data collection. Qualified Researchers can explore, analyze, and download patient-reported outcomes (PROs) data and Parkinson's disease- related genetic variants at . The full Fox Insight genetic data set, including approximately 600,000 single nucleotide polymorphisms (SNPs), can be requested separately with institutional review and are described outside of this data descriptor.
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页数:9
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