10-acetoxy-9-chloro-8,9-dehydrothymol and further thymol derivatives from Arnica sachalinensis

被引:26
作者
Passreiter, CM
Matthiesen, U
Willuhn, G
机构
[1] Univ Dusseldorf, Inst Pharmazeut Biol, D-40225 Dusseldorf, Germany
[2] Univ Dusseldorf, Zent Inst Klin Chem, D-40225 Dusseldorf, Germany
[3] Univ Dusseldorf, Labs Diagnost Med Einrichtungen, D-40225 Dusseldorf, Germany
关键词
Arnica sachalinensis; Asteraceae; flavers; thymol derivatives; thymol epoxides; chlorinated thymol derivative;
D O I
10.1016/S0031-9422(98)00242-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The new thymol derivatives, 10-acetoxy-9-chloro-8,9-dehydrothymol, 10-acetoxy-8,9-dehydrothymol, 10-isobutyryloxy-8,9-dehydrothymol and 9-acetoxy-thymol, were isolated from flowerheads of Arnica sachalinensis and identified by their mass and NMR spectra. Furthermore, six new and five known thymol derivatives were identified as minor compounds mainly by TLC and GC-mass spectrometric analysis. (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码:777 / 781
页数:5
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