Viruses in cancer therapy - from benchwarmers to quarterbacks

被引：16

作者：

Peruzzi, Pierpaolo

Chiocca, E. Antonio ^{[1
]}

机构：

[1] Brigham & Womens Hosp, Harvey Cushing Neurooncol Labs, Dept Neurosurg, 75 Francis St, Boston, MA 02115 USA

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2018年 / 15卷 / 11期

关键词：

IMMUNOTHERAPY; ADJUVANT; TRIAL;

D O I：

10.1038/s41571-018-0077-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A recent clinical trial of a virotherapy approach, consisting of an engineered poliovirus, has provided evidence of apparently durable responses in patients with recurrent glioblastoma. The results of this trial and others indicate that virotherapy might be an effective tool in anticancer immunotherapy. Yet, caution must be exercised until appropriately powered randomized clinical trials truly show efficacy.

引用

页码：657 / 658

页数：2

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