Copper-Catalyzed Intermolecular Aminooxygenation of Styrenes using N-Fluorobenzenesulfonimide and Simple Alcohols

被引：30

作者：

Herrera-Leyton, Camilo ^{[1
]}

Madrid-Rojas, Matias ^{[1
]}

Lopez, Jhon J. ^{[1
]}

Canete, Alvaro ^{[1
]}

Hermosilla-Ibanez, Patricio ^{[2
,3
]}

Perez, Edwin G. ^{[1
]}

机构：

[1] Pontificia Univ Catolica Chile, Dept Organ Chem, Fac Chem, Ave Vicuna Mackenna 4860,Casilla 306,Correo 22, Santiago, Chile

[2] Univ Santiago Chile USA CH, Fac Quim & Biol, Santiago, Chile

[3] CEDENNA, Ctr Desarrollo Nanotecnol, Santiago, Chile

来源：

CHEMCATCHEM | 2016年 / 8卷 / 12期

关键词：

aminooxygenation; copper; neuronal ligands; radicals; regioselectivity; CARBOXYLIC-ACIDS; BOND FORMATION; ALKENES; OLEFINS; AMINOHYDROXYLATION; OXYAMINATION; DERIVATIVES; AMINOACETOXYLATION; AMINOFLUORINATION; AMINOPALLADATION;

D O I：

10.1002/cctc.201600254

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The mild and fast copper-catalyzed radical and regioselective aminoalkoxylation of styrenes by using N-fluorobenzenesulfonimide and simple alcohols as nitrogen and alkoxy sources, respectively, was investigated. The aminoalkoxylated products obtained could be used in the synthesis of new compounds with possible activity as neurotransmitter receptor ligands.

引用

页码：2015 / 2018

页数：4

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