Insights into Borrelia miyamotoi infection from an untreated case demonstrating relapsing fever, monocytosis and a positive C6 Lyme serology

被引:34
作者
Sudhindra, Praveen [1 ]
Wang, Guiqing [2 ,3 ]
Schriefer, Martin E. [4 ]
McKenna, Donna
Jian Zhuge [2 ,3 ]
Krause, Peter J. [5 ,6 ]
Marques, Adriana R. [7 ]
Wormser, Gary P. [1 ]
机构
[1] New York Med Coll, Div Infect Dis, Valhalla, NY 10595 USA
[2] New York Med Coll, Dept Pathol, Valhalla, NY 10595 USA
[3] Westchester Med Ctr, Dept Pathol & Clin Labs, Valhalla, NY 10595 USA
[4] Ctr Dis Control & Prevent, Ft Collins, CO USA
[5] Yale Univ, Yale Sch Publ Hlth, New Haven, CT USA
[6] Yale Univ, Yale Sch Med, New Haven, CT USA
[7] NIAID, Lab Clin Infect Dis, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
Borrelia; Borrelia Miyamotoi; Lyme disease; C6; serology; Monocytosis; Relapsing fever; UNITED-STATES; DISEASE; MENINGOENCEPHALITIS; BURGDORFERI; SYPHILIS; VECTOR; EUROPE; JAPAN; ASSAY;
D O I
10.1016/j.diagmicrobio.2016.06.015
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We describe a patient from the United States with PCR- and serology-confirmed Borrelia miyamotoi infection who recovered without antibiotics. Our findings suggest that B. miyamotoi infection may cause relapsing fever, blood monocytosis and antibody reactivity to the C6 peptide. Further studies are required to better define the spectrum of clinical and laboratory findings for this emerging tick-transmitted infection. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:93 / 96
页数:4
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