Neuroscience of Compulsive Eating Behavior

被引：43

作者：

Moore, Catherine F. ^{[1
,2
]}

Sabino, Valentina ^{[1
]}

Koob, George F. ^{[3
]}

Cottone, Pietro ^{[1
]}

机构：

[1] Boston Univ, Sch Med, Dept Pharmacol & Psychiat, Lab Addict Disorders, Boston, MA 02118 USA

[2] Boston Univ, Sch Med, Grad Program Neurosci, Boston, MA 02118 USA

[3] NIAAA, NIH, Bethesda, MD USA

来源：

FRONTIERS IN NEUROSCIENCE | 2017年 / 11卷

基金：

美国国家卫生研究院;

关键词：

compulsive; addiction; eating; habit; withdrawal; inhibitory control; OPIOID RECEPTOR ANTAGONIST; PALATABLE FOOD; FEMALE RATS; INHIBITORY CONTROL; PREFRONTAL CORTEX; STRIATAL RESPONSE; DOPAMINE RELEASE; SEEKING BEHAVIOR; SUCROSE SOLUTION; CHRONIC STRESS;

D O I：

10.3389/fnins.2017.00469

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A systematic characterization of compulsivity in pathological forms of eating has been proposed in the context of three functional domains: (1) habitual overeating; (2) overeating to relieve a negative emotional state; and (3) overeating despite aversive consequences. In this review, we provide evidence supporting this hypothesis and we differentiate the nascent field of neurocircuits and neurochemical mediators of compulsive eating through their underlying neuropsychobiological processes. A better understanding of the neurobiological mechanisms that lead to compulsive eating behavior can improve behavioral and pharmacological intervention for disorders of pathological eating.

引用

页数：8

共 84 条

[1]

[Anonymous], DIAGN STAT MAN MENT

[2]

[Anonymous], RES DOM CRIT RDOC

[3] After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance [J].

Avena, Nicole M. ;

Bocarsly, Miriam E. ;

Rada, Pedro ;

Kim, Agnes ;

Hoebel, Bartley G. .

PHYSIOLOGY & BEHAVIOR, 2008, 94 (03) :309-315

[4] Divergent Neural Substrates of Inhibitory Control in Binge Eating Disorder Relative to Other Manifestations of Obesity [J].

Balodis, Iris M. ;

Molina, Nathan D. ;

Kober, Hedy ;

Worhunsky, Patrick D. ;

White, Marney A. ;

Sinha, Rajita ;

Grilo, Carlos M. ;

Potenza, Marc N. .

OBESITY, 2013, 21 (02) :367-377

[5] Body mass correlates inversely with inhibitory control in response to food among adolescent girls: An fMRI study [J].

Batterink, Laura ;

Yokum, Sonja ;

Stice, Eric .

NEUROIMAGE, 2010, 52 (04) :1696-1703

[6] Cocaine seeking habits depend upon doparnine-dependent serial connectivity linking the ventral with the dorsal striatum [J].

Belin, David ;

Everitt, Barry J. .

NEURON, 2008, 57 (03) :432-441

[7] Characterization of a shortened model of diet alternation in female rats: effects of the CB1 receptor antagonist rimonabant on food intake and anxiety-like behavior [J].

Blasio, Angelo ;

Rice, Kenner C. ;

Sabino, Valentina ;

Cottone, Pietro .

BEHAVIOURAL PHARMACOLOGY, 2014, 25 (07) :609-617

[8] Opioid system in the medial prefrontal cortex mediates binge-like eating [J].

Blasio, Angelo ;

Steardo, Luca ;

Sabino, Valentina ;

Cottone, Pietro .

ADDICTION BIOLOGY, 2014, 19 (04) :652-662

[9] Rimonabant Precipitates Anxiety in Rats Withdrawn from Palatable Food: Role of the Central Amygdala [J].

Blasio, Angelo ;

Iemolo, Attilio ;

Sabino, Valentina ;

Petrosino, Stefania ;

Steardo, Luca ;

Rice, Kenner C. ;

Orlando, Pierangelo ;

Iannotti, Fabio Arturo ;

Di Marzo, Vincenzo ;

Zorrilla, Eric P. ;

Cottone, Pietro .

NEUROPSYCHOPHARMACOLOGY, 2013, 38 (12) :2498-2507

[10] Addiction-like Synaptic Impairments in Diet-Induced Obesity [J].

Brown, Robyn Mary ;

Kupchik, Yonatan Michael ;

Spencer, Sade ;

Garcia-Keller, Constanza ;

Spanswick, David C. ;

Lawrence, Andrew John ;

Simonds, Stephanie Elise ;

Schwartz, Danielle Joy ;

Jordan, Kelsey Ann ;

Jhou, Thomas Clayton ;

Kalivas, Peter William .

BIOLOGICAL PSYCHIATRY, 2017, 81 (09) :797-806

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