The Use of Cannabis and Its Effects on Postpartum Depression

被引：2

作者：

Ayisire, Oghenetega E. ^{[1
]}

Okobi, Okelue E. ^{[2
]}

Adaralegbe, Ngozi J. ^{[3
]}

Adeosun, Adeyemi A. ^{[4
]}

Sood, Divyaanshi ^{[5
]}

Onyechi, Nkemputaife P. ^{[6
]}

Agazie, Ogochukwu ^{[7
]}

Shittu, Hameed O. ^{[8
]}

Akinsola, Zainab ^{[9
]}

Ninaji, Chukwudike G. ^{[10
]}

Owolabi, Oluwasayo J. ^{[11
]}

Umeh, Nneka J. ^{[12
]}

Imobighe, Imolikhe C. ^{[13
]}

Adedoyin, Adewale M. ^{[14
]}

Usman, Madinah ^{[15
]}

机构：

[1] Univ South Wales, Psychiat, Pontypridd, Wales

[2] Lakeside Med Ctr, Family Med, Belle Glade, FL 33430 USA

[3] Univ Connecticut, Allied Hlth Sci, Waterbury, CT USA

[4] Mayo Clin, Mol Pharmacol & Expt Therapeut, Rochester, MN USA

[5] Dayanand Med Coll & Hosp, Oncol, Ludhiana, India

[6] Univ Hosp Cleveland Med Ctr, Internal Med, Cleveland, OH USA

[7] Coll Med Univ Lagos, Gen Phys, Idi Araba, Nigeria

[8] Fed Med Ctr, Internal Med, Abeokuta, Nigeria

[9] Windsor Univ Sch Med, Internal Med Family Med, Toronto, ON, Canada

[10] Windsor Univ Sch Med, Internal Med Family Med, Chicago, IL USA

[11] Lugansk Sate Med Univ, Psychiat, Lugansk, Ukraine

[12] Brooklyn Queens Nursing Home, Gen Med, New York, NY USA

[13] Irrua Specialist Teaching Hosp, Obstet & Gynecol, Irrua, Nigeria

[14] Lagos State Univ Teaching Hosp, Internal Med, Ikeja, Nigeria

[15] Kharkiv Natl Med Univ, Med, Kharkiv, Ukraine

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 08期

关键词：

depression; peripartum depression; tetrahydrocannabinol (thc); post partum depression; cannabis use; NEUROBIOLOGY; RESPONSES;

D O I：

10.7759/cureus.27926

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cannabis use and depression management have been studied, with a preponderance of exacerbating effects, but there are few studies on postpartum depression (PPD). Depression affects a significant number of women, with a portion of it manifesting as PPD in childbearing women in the United States each year. The pharmacologic management approaches have disadvantages such as side effects, cost-benefit ratio, contraindications, use reluctance, medication adherence, and stigmatization in patients. Anecdotal claims of medical cannabis' therapeutic benefits have led to widespread legalization in several regions, making cannabis and its extracts a possible alternative. Cannabis is widely used during pregnancy and in general. Even though substance use disorders exacerbating depression symptoms have been reported, there are increasing reports and evidence about the therapeutic benefit of dose-dependent cannabis or its extracts in some depression symptoms, such as acute psychosocial stress relief, its purported anxiolytic effect, appetite, and sleep quality, thus stimulating more interest that may be inferred to depression. PPD marijuana use is unclear. This paper reviewed works of literature that claimed cannabis' therapeutic benefit in treating depression and, by extension, PPD. Our findings show the link between cannabis and PPD has not been fully explored. Self-reported studies link marijuana uses to positive mood, anxiety relief, sleep regulation, nausea and vomiting reduction, and appetite stimulation-all PPD symptoms. Others opposed postpartum marijuana use.

引用

页数：9

共 55 条

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American Psychiatric Association, 2022, What is Peripartum Depression (formerly postpartum)?

[2]

American Psychiatric Association, 2013, AM PSYCHIATRIC ASS, V21, P591

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