Caspase cleavage is not for everyone

被引：21

作者：

Johnson, Carrie E. ^{[1
]}

Kornbluth, Sally ^{[1
]}

机构：

[1] Duke Univ, Dept Pharmacol & Canc Biol, Durham, NC 27710 USA

来源：

CELL | 2008年 / 134卷 / 05期

关键词：

D O I：

10.1016/j.cell.2008.08.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During apoptosis, caspases cleave cellular substrates to break down and package the apoptotic cell for removal. Reporting in Cell, Mahrus et al. (2008) and Dix et al. (2008) use new approaches that identify hundreds of previously unrecognized caspase substrates, many of which appear to produce polypeptide fragments with potentially new functional activities.

引用

页码：720 / 721

页数：2

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