Isobutyraldehyde in the synthesis of isopropyl-substituted 4H-pyrans, 1,4-dihydropyrano[2,3-c]pyrazole, 1,4-dihydropyridines, and cyclobutane

被引：15

作者：

Dyachenko, VD ^{[1
]}

Chernega, AN

机构：

[1] Shevchenko Natl Pedagog Univ, Lugansk, Ukraine

[2] Natl Acad Sci, Inst Organ Chem, Kiev, Ukraine

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2005年 / 75卷 / 06期

关键词：

D O I：

10.1007/s11176-005-0351-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Condensation of isobutyraldehyde with CH acids, such as acetoacetanilide, dimedone, acetoacetamide, ethyl benzoylacetate, resorcinol, cyanoacetic acid, malononitrile, 3-methyl-1-ethyl-2-pyrazolin-5-one, benzoylacetone, and cyanoacetamide, in the presence of amines gave isopropyl-substituted 4H-pyrans, 1,4dihydropyrano[2,3-c]pyrazole, 4H-benzo[b]pyranes, 1,4-dihydropyridines, and 1,1-dicyano-2-(1-cyano-lethoxycarbonyl)methyl-4-isopropyl-3,3-dimethyleyclobutane. The structure of the latter product was studied by X-ray diffraction analysis.

引用

收藏

页码：952 / 960

页数：9

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