Strategies for Hepatocellular Carcinoma Therapy and Diagnostics: Lessons Learned from High Throughput and Profiling Approaches

被引：47
作者：
Breuhahn, Kai [1 ]
Gores, Gregory [2 ]
Schirmacher, Peter [1 ]
机构：
[1] Univ Hosp, Inst Pathol, D-69120 Heidelberg, Germany
[2] Mayo Clin, Mayo Coll Med, Rochester, MN USA
来源：
HEPATOLOGY | 2011年 / 53卷 / 06期
关键词：
GROWTH-FACTOR-BETA; HEPATITIS-B; LIVER-CANCER; HUMAN HEPATOCARCINOGENESIS; MICRORNA EXPRESSION; MULTISTEP HEPATOCARCINOGENESIS; OLIGONUCLEOTIDE MICROARRAY; MOLECULAR PATHOGENESIS; ABERRANT METHYLATION; GENETIC ALTERATIONS;
D O I：
10.1002/hep.24313
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Over the last decade, numerous small and high-dimensional profiling analyses have been performed in human hepatocellular carcinoma (HCC), which address different levels of regulation and modulation. Because comprehensive analyses are lacking, the following review summarizes some of the general results and compares them with insights from other tumor entities. Particular attention is given to the impact of these results on future diagnostic and therapeutic approaches. (HEPATOLOGY 2011;53:2111-2120)
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收藏
页码：2111 / 2120
页数：10
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