Multifocal Nodular Periostitis Associated With Prolonged Voriconazole Therapy in a Lung Transplant Recipient

被引：31

作者：

Ayub, Asad ^{[1
]}

Kenney, Charles V. ^{[2
]}

McKiernan, Fergus E. ^{[3
]}

机构：

[1] Mem Hosp, Dept Internal Med, Jacksonville, FL 32216 USA

[2] Marshfield Clin Fdn Med Res & Educ, Dept Radiol, Marshfield, WI USA

[3] Marshfield Clin Fdn Med Res & Educ, Ctr Bone Dis, Marshfield, WI USA

来源：

JCR-JOURNAL OF CLINICAL RHEUMATOLOGY | 2011年 / 17卷 / 02期

关键词：

voriconazole; periostitis; HYPERTROPHIC OSTEOARTHROPATHY; FLUOROSIS; BONE; FLUORIDE;

D O I：

10.1097/RHU.0b013e31820aff12

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of painful, nodular periostitis in a lung transplant recipient on long-term voriconazole therapy. Symptoms, signs, and laboratory abnormalities resolved quickly after drug withdrawal. The presentation more closely resembles periostitis deformans than hypertrophic osteoarthropathy, suggesting that the fluoride moiety of voriconazole may be pathogenic for this condition. Clinicians should be aware of this association.

引用

页码：73 / 75

页数：3

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