Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts

被引：13
作者：
Kirken, RA
Erwin-Cohen, R
Behbod, F
Wang, ME
Stepkowski, SM
Kahan, BD
机构：
[1] Univ Texas, Dept Integrat Biol & Pharmacol, Houston, TX USA
[2] Univ Texas, Div Immunol & Organ Transplant, Houston, TX USA
来源：
TRANSPLANTATION PROCEEDINGS | 2001年 / 33卷 / 1-2期
关键词：
D O I：
10.1016/S0041-1345(00)02791-3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：95 / 95
页数：1
相关论文
共 3 条
[1]   Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells [J].
Kirken, RA ;
Erwin, RA ;
Taub, D ;
Murphy, WJ ;
Behbod, F ;
Wang, LH ;
Pericle, F ;
Farrar, WL .
JOURNAL OF LEUKOCYTE BIOLOGY, 1999, 65 (06) :891-899
[2]   JAKS AND STATS: Biological implications [J].
Leonard, WJ ;
O'Shea, JJ .
ANNUAL REVIEW OF IMMUNOLOGY, 1998, 16 :293-322
[3]   Localization of cryptic tolerogenic epitopes in the alpha(1)-helical region of the RT1.A(U) alloantigen [J].
Wang, M ;
Stepkowski, SM ;
Yu, J ;
Wang, ME ;
Kahan, BD .
TRANSPLANTATION, 1997, 63 (10) :1373-1379
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