Pathogenesis and management of HIV/TB co-infection in Asia

被引：17
作者：
Goldfeld, Anne
Ellner, Jerrold J. [1 ]
机构：
[1] CBR Inst, Cambridge, MA USA
[2] Harvard Univ, Sch Med, Cambridge, MA 02138 USA
[3] Univ Med & Dent New Jersey, New Jersey Med Sch, Newark, NJ 07103 USA
来源：
TUBERCULOSIS | 2007年 / 87卷
关键词：
TB-HIV; atypical forms; Vietnam; integrated control and research programs in Cambodia;
D O I：
10.1016/j.tube.2007.05.003
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
HIV infection increases the risk of reactivation of latent tuberculosis (TB), progression of a new infection or re-infection to active disease, and acceleration of the natural course of the disease with a more rapid spread of strains, including those that are drug resistant, in the community. TB also accelerates the course of HIV-induced disease by activating viral replication and accentuating the decline in CD4 T cell counts. In this chapter, TB-HIV coinfection is discussed in the context of the situation in Vietnam, particularly Ho Chi Minh City, the creation of a well-integrated TB control and research programs in Cambodia, and the broad principles of the co-management of TB/HIV particularly in the context of the associated atypical forms of pulmonary TB (PTB), increased non-PTB and the frequency of acid fast smear negative cases. (c) 2007 Published by Elsevier Ltd.
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收藏
页码：S26 / S30
页数：5
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