Synthesis of 4-aryl substituted 3,4-dihydropyrimidinones using silica-chloride under solvent free conditions

被引：91

作者：

Karade, Hitendra N. ^{[1
]}

Sathe, Manisha ^{[1
]}

Kaushik, M. P. ^{[1
]}

机构：

[1] Def Res & Dev Estab, Proc Technol Dev Div, Disc Ctr, Gwalior 474002, MP, India

来源：

MOLECULES | 2007年 / 12卷 / 07期

关键词：

biginelli reaction; dihydropyrimidinones; silica chloride; solvent free;

D O I：

10.3390/12071341

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.

引用

页码：1341 / 1351

页数：11

共 37 条

[21] Lanthanide triflate catalyzed Biginelli reaction. One-pot synthesis of dihydropyrimidinones under solvent-free conditions [J].

Ma, Y ;

Qian, CT ;

Wang, LM ;

Yang, M .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (12) :3864-3868

[22] DEOXYGENATION OF SULFOXIDES WITH SILICA CHLORIDE [J].

MOHANAZADEH, F ;

MOMENI, AR ;

RANJBAR, Y .

TETRAHEDRON LETTERS, 1994, 35 (33) :6127-6128

[23]

Onofrio F. D, 1985, SYNTHESIS-STUTTGART, P1159

[24] NOVEL ALKALOIDS FROM THE SPONGE BATZELLA SP - INHIBITORS OF HIV GP120-HUMAN CD4 BINDING [J].

PATIL, AD ;

KUMAR, NV ;

KOKKE, WC ;

BEAN, MF ;

FREYER, AJ ;

DEBROSSE, C ;

MAI, S ;

TRUNEH, A ;

FAULKNER, DJ ;

CARTE, B ;

BREEN, AL ;

HERTZBERG, RP ;

JOHNSON, RK ;

WESTLEY, JW ;

POTTS, BCM .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (05) :1182-1188

[25] Ionic liquids catalyzed Biginelli reaction under solvent-free conditions [J].

Peng, JJ ;

Deng, YQ .

TETRAHEDRON LETTERS, 2001, 42 (34) :5917-5919

[26] Indium(III) chloride-catalyzed one-pot synthesis of dihydropyrimidinones by a three-component coupling of 1,3-dicarbonyl compounds, aldehydes, and urea: An improved procedure for the Biginelli reaction [J].

Ranu, BC ;

Hajra, A ;

Jana, U .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (19) :6270-6272

[27] Silica sulfuric acid and silica chloride as efficient reagents for organic reactions [J].

Salehi, Peyman ;

Zolfigol, Mohammad Ali ;

Shirini, Farhad ;

Baghbanzadeh, Mostafa .

CURRENT ORGANIC CHEMISTRY, 2006, 10 (17) :2171-2189

[28] An efficient method for the esterification of phosphonic and phosphoric acids using silica chloride [J].

Sathe, M ;

Gupta, AK ;

Kaushik, MP .

TETRAHEDRON LETTERS, 2006, 47 (18) :3107-3109

[29] An efficient method for the esterification of amino acids using silica chloride [J].

Sathe, Manisha ;

Kaushik, M. P. .

CATALYSIS COMMUNICATIONS, 2006, 7 (09) :644-646

[30] Oxidation of thiols to disulfides using silica chloride as a heterogeneous catalyst [J].

Sathe, Manisha ;

Ghorpade, Ramarao ;

Kaushik, Mahabir Parshad .

CHEMISTRY LETTERS, 2006, 35 (09) :1048-1049

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