Regioselective C-H Borylation of Heteroaromatic Aldimines with Iridium Complexes

被引：5

作者：

Sasaki, Ikuo

Ikeda, Toshiki

Amou, Tatsunosuke

Taguchi, Jumpei

Ito, Hajime ^{[1
]}

Ishiyama, Tatsuo ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Engn, Div Appl Chem, Kita Ku, Kita 13 Nishi 8, Sapporo, Hokkaido 0608628, Japan

来源：

SYNLETT | 2016年 / 27卷 / 10期

关键词：

iridium; catalysis; borylation; heteroarenes; regioselectivity; aldimines; DIRECTED ORTHO BORYLATION; CATALYZED BORYLATION; ARENES; HETEROARENES; FUNCTIONALIZATION; ACTIVATION; BIS(PINACOLATO)DIBORON; HETEROCYCLES; BONDS; PINACOLBORANE;

D O I：

10.1055/s-0035-1561578

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An iridium-catalyzed regioselective C-H borylation of pentafluoroaniline-derived heteroaromatic aldimines has been developed. Various heteroaromatic aldimines underwent borylation by bis(pinacolato)diboron to afford the corresponding borylated products in good yields in the presence of an iridium complex formed in situ from bis(cyclooctadienyl)(methoxy)iridium {[Ir(OMe)(cod)](2)} and 1,10-phenanthroline.

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页码：1582 / 1586

页数：5

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