N-Heterocyclic carbene-catalyzed [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines

被引：48
|
作者：
Gao, Zhong-Hua [1 ]
Chen, Xiang-Yu [1 ]
Cheng, Jin-Tang [1 ]
Liao, Wei-Lin [2 ]
Ye, Song [1 ]
机构：
[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China
[2] Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 45期
基金：
美国国家科学基金会;
关键词：
HIGHLY ENANTIOSELECTIVE SYNTHESIS; DIELS-ALDER REACTIONS; STEREOSELECTIVE ANNULATION REACTIONS; AZA-BENZOIN REACTION; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; 4+2 CYCLOADDITION; ORGANOCATALYTIC ACTIVATION; 1,3-DIPOLAR CYCLOADDITION; COOPERATIVE CATALYSIS;
D O I：
10.1039/c5cc01238d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An N-heterocyclic carbene-catalyzed enantioselective [2+3] cyclocondensation of alpha-chloroaldehydes with azomethine imines was developed. The corresponding pyrazolidinones were obtained in good yields with moderate to good diastereoselectivities and excellent enantioselectivities.
引用
收藏
页码：9328 / 9331
页数：4
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