Cryptococcal Pleuritis Presenting with Lymphocyte-predominant and High Levels of Adenosine Deaminase in Pleural Effusions Coincident with Pulmonary Tuberculosis

被引：7

作者：

Kushima, Yoshitomo ^{[1
]}

Takizawa, Hidenori ^{[1
]}

Machida, Yasutaka ^{[2
]}

Umetsu, Takafumi ^{[1
]}

Ikeda, Naoya ^{[1
]}

Miyoshi, Masaaki ^{[1
]}

Chibana, Kazuyuki ^{[1
]}

Shimizu, Yasuo ^{[1
]}

Takemasa, Akihiro ^{[1
]}

Ishii, Yoshiki ^{[1
]}

机构：

[1] Dokkyo Med Univ, Dept Pulm & Clin Immunol, Mibu, Tochigi, Japan

[2] Nasu Red Cross Hosp, Otawara, Tochigi, Japan

来源：

INTERNAL MEDICINE | 2018年 / 57卷 / 01期

关键词：

cryptococcal pleuritis; pulmonary tuberculosis; co-infection; adenosine deaminase; cryptococcal antigen test; IMMUNE-DEFICIENCY-SYNDROME; NEOFORMANS; MANIFESTATION; FLUCONAZOLE; INVOLVEMENT; DIAGNOSIS; DISEASES; THERAPY; PATIENT; UPDATE;

D O I：

10.2169/internalmedicine.9020-17

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Co-infection with cryptococcus and tuberculosis has rarely been reported. We herein report a case of an 80-year-old man with cryptococcal pleuritis concurrent with pulmonary tuberculosis. He was admitted for progression of left pleural effusion and consolidation in the left upper lobe. Culture for Mycobacterium tuberculosis was positive in sputum, and analyses of pleural effusion revealed lymphocyte-predominant high levels of adenosine deaminase (ADA). Medical thoracoscopy revealed massive infiltration of Cryptococcus neoformans in pleura without granuloma. This is the first case report of cryptococcal pleuritis coincident with pulmonary tuberculosis. Cryptococcal pleuritis should be ruled out when the adenosine deaminase levels are elevated in pleural effusion.

引用

页码：115 / 120

页数：6

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