Precocious puberty in an infant

被引:0
|
作者
Lindenthal, V. [1 ]
Kolb, R. [1 ]
Loening, L. [1 ]
Leuschner, I. [2 ]
Morcate-Cabrera, J. [3 ]
Raab, H. -R. [4 ]
von Schweinitz, D. [5 ]
Mueller, H. L. [1 ]
机构
[1] Klinikum Oldenburg, Zentrum Kinder & Jugendmed, Klin Allgemeine Kinderheilkunde, D-26133 Oldenburg, Germany
[2] Univ Klinikum Schleswig Holstein, Inst Pathol, Sekt Kinderpathol, Lubeck, Germany
[3] Klinikum Oldenburg, Klin Kinderchirurg, D-26133 Oldenburg, Germany
[4] Klinikum Oldenburg, Klin Allgemein & Visceralchirurg, D-26133 Oldenburg, Germany
[5] Univ Munich, Kinderchirurg Klin & Poliklin, D-80539 Munich, Germany
关键词
Hepatoblastoma; Pseudopubertas praecox; Precocious puberty; Paraneoplastic hormone production; Hyperandrogenism;
D O I
10.1007/s00112-011-2557-5
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
In rare cases precocious puberty is induced by paraneoplastic production of sex steroids. Therefore, a careful inspection of the genital organs should routinely be included in a pediatric clinical examination. Differential diagnosis of precocious puberty includes adrenocortical tumors and adrenal enzyme deficiencies as well as primary hepatic tumors with endocrine activity in addition to central causes. In the case described here the cause was a hepatoblastoma with paraneoplastic production of testosterone.
引用
收藏
页码:106 / 108
页数:3
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