Reversible dilated cardiomyopathy related to amphotericin B therapy

被引：28

作者：

Danaher, PJ

Cao, MK

Anstead, GM

Dolan, MJ

DeWitt, CC

机构：

[1] David Grant USAF Med Ctr, Dept Infect Dis, Travis AFB, CA 94535 USA

[2] David Grant USAF Med Ctr, Dept Cardiol, Travis AFB, CA 94535 USA

[3] Dept Vet Affairs Med Ctr, Med Serv, S Texas Hlth Care Syst, San Antonio, TX 78229 USA

[4] Wilford Hall USAF Med Ctr, Dept Infect Dis, Lackland AFB, TX 78236 USA

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2004年 / 53卷 / 01期

关键词：

posaconazole; coccidioidomycosis; Coccidioides immitis;

D O I：

10.1093/jac/dkg472

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We describe a patient who developed dilated cardiomyopathy and clinical congestive heart failure after 2 months of therapy with amphotericin B (AmB) for disseminated coccidioidomycosis. His echocardiographic abnormalities and heart failure resolved after posaconazole was substituted for AmB. It is important to recognize the rare and potentially reversible toxicity of AmB.

引用

页码：115 / 117

页数：3

共 19 条

[11] Activity of the triazole SCH 56592 against disseminated murine coccidioidomycosis [J].