Reversible dilated cardiomyopathy related to amphotericin B therapy

被引：28
作者：
Danaher, PJ
Cao, MK
Anstead, GM
Dolan, MJ
DeWitt, CC
机构：
[1] David Grant USAF Med Ctr, Dept Infect Dis, Travis AFB, CA 94535 USA
[2] David Grant USAF Med Ctr, Dept Cardiol, Travis AFB, CA 94535 USA
[3] Dept Vet Affairs Med Ctr, Med Serv, S Texas Hlth Care Syst, San Antonio, TX 78229 USA
[4] Wilford Hall USAF Med Ctr, Dept Infect Dis, Lackland AFB, TX 78236 USA
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2004年 / 53卷 / 01期
关键词：
posaconazole; coccidioidomycosis; Coccidioides immitis;
D O I：
10.1093/jac/dkg472
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We describe a patient who developed dilated cardiomyopathy and clinical congestive heart failure after 2 months of therapy with amphotericin B (AmB) for disseminated coccidioidomycosis. His echocardiographic abnormalities and heart failure resolved after posaconazole was substituted for AmB. It is important to recognize the rare and potentially reversible toxicity of AmB.
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收藏
页码：115 / 117
页数：3
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