Water as an active constituent in cell biology

被引:1777
作者
Ball, Philip [1 ]
机构
[1] Nature, London N1 9XW, England
关键词
D O I
10.1021/cr068037a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A review regarding the case where water is considered to be a versatile and adaptive component of the cell that engages in a wide range of biomolecular interactions is discussed. A focus will be given on the distinctions between generic and specific behaviors of biological water to show the "uniqueness" of water to life. Specific topics to be discussed include: water as a liquid and solvent, the aqueous environment of the cell, the nonspecific effects and the specific roles of water in structure and function regarding protein hydration, and lastly, the relation of water and nucleic acids.
引用
收藏
页码:74 / 108
页数:35
相关论文
共 445 条
[1]   THE GROTTHUSS MECHANISM [J].
AGMON, N .
CHEMICAL PHYSICS LETTERS, 1995, 244 (5-6) :456-462
[2]   Aquaporin water channels (Nobel lecture) [J].
Agre, P .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (33) :4278-4290
[3]   PROTON CONDUCTANCE BY THE GRAMICIDIN WATER WIRE - MODEL FOR PROTON CONDUCTANCE IN THE F1F0 ATPASES [J].
AKESON, M ;
DEAMER, DW .
BIOPHYSICAL JOURNAL, 1991, 60 (01) :101-109
[4]   Structure of hydrophobic hydration of benzene and hexafluorobenzene from first principles [J].
Allesch, Markus ;
Schwegler, Eric ;
Galli, Giulia .
JOURNAL OF PHYSICAL CHEMISTRY B, 2007, 111 (05) :1081-1089
[5]   Gain-of-function mutations reveal expanded intermediate states and a sequential action of two gates in MscL [J].
Anishkin, A ;
Chiang, CS ;
Sukharev, S .
JOURNAL OF GENERAL PHYSIOLOGY, 2005, 125 (02) :155-170
[6]   Water dynamics and dewetting transitions in the small mechanosensitive channel MscS [J].
Anishkin, A ;
Sukharev, S .
BIOPHYSICAL JOURNAL, 2004, 86 (05) :2883-2895
[7]  
[Anonymous], HYDROGEN BONDING, DOI DOI 10.1016/B978-0-08-009140-2.50004-X
[8]  
[Anonymous], 1913, The fitness of the environment
[9]   Role of interfacial water in the molecular dynamics-simulated dynamical transition of plastocyanin [J].
Arcangeli, C ;
Bizzarri, AR ;
Cannistraro, S .
CHEMICAL PHYSICS LETTERS, 1998, 291 (1-2) :7-14
[10]   Colloquium:: Scaled particle theory and the length scales of hydrophobicity [J].
Ashbaugh, HS ;
Pratt, LR .
REVIEWS OF MODERN PHYSICS, 2006, 78 (01) :159-178