Regioselective Construction of Coumarin-1,2,4-triazines via a Cs2CO3-Catalyzed [3+3] Cycloaddition Reaction

被引：1
作者：
Liu, Xuan-Yu [1 ,2 ]
Zhang, Fa-Guang [1 ,2 ]
Ma, Jun-An [1 ,2 ,3 ]
机构：
[1] Tianjin Univ, Frontiers Sci Ctr Synthet Biol, Dept Chem, Tianjin Key Lab Mol Optoelect Sci,Minist Educ, Tianjin 300072, Peoples R China
[2] Tianjin Univ, Tianjin Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China
[3] Tianjin Univ, Joint Sch Natl Univ Singapore & Tianjin Univ, Int Campus, Fuzhou 350207, Peoples R China
来源：
SYNLETT | 2022年 / 33卷 / 11期
基金：
中国国家自然科学基金;
关键词：
triazine; cycloaddition; diazo reagent; coumarin; regioselectivity; POTENTIAL FLUOROGENIC REAGENTS; DIELS-ALDER REACTIONS; 1,2,4-TRIAZINE DERIVATIVES; ANNULATION REACTIONS; STABLE DIAZOALKANES; ACCESS; 4-DIAZOMETHYL-7-METHOXYCOUMARIN; COUMARIN;
D O I：
10.1055/a-1828-7504
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A cesium carbonate (Cs2CO3)-catalyzed [3+3] cycloaddition reaction of coumarin-diazo reagents with glycine imino esters is established to produce tetrahydro-1,2,4-triazines in good yields with excellent regioselectivity. One-pot cycloaddition/oxidation protocol could further provide practical access to a series of new coumarin-decorated 1,2,4-triazines.
引用
收藏
页码：1097 / 1101
页数：5
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