The outcome of twin reversed arterial perfusion sequence diagnosed in the first trimester

被引:118
作者
Lewi, Liesbeth [1 ,2 ]
Valencia, Catalina [1 ]
Gonzalez, Esperanza [1 ]
Deprest, Jan [2 ]
Nicolaides, Kypros H. [1 ]
机构
[1] Kings Coll Hosp London, Harris Birthright Res Ctr Fetal Med, London, England
[2] Univ Hosp Leuven, Div Woman, Dept Woman & Child, Louvain, Belgium
关键词
acardiac; monochorionic twin pregnancy; TRAP; twin reversed arterial perfusion; FETAL; AMNIOCENTESIS; RISK;
D O I
10.1016/j.ajog.2010.04.018
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: The aim of this study was to document the mortality of twin reversed arterial perfusion (TRAP) sequence from the first trimester to planned intervention at 16-18 weeks. STUDY DESIGN: A retrospective review was performed of the outcome of monochorionic twin pregnancies diagnosed with twin reversed arterial perfusion sequence in the first trimester. RESULTS: Twenty-six pregnancies were diagnosed with twin reversed arterial perfusion sequence in the first trimester: 2 opted for termination of pregnancy and 24 opted for prophylactic intervention to arrest the reversed flow, which was planned at 16-18 weeks. In 8 of 24 (33%) pregnancies, spontaneous death of the pump twin occurred between diagnosis and planned intervention. In 5 of 24 (21%), there was a spontaneous arrest of flow; whereas, in 11 (46%) there was persistent flow toward the acardiac twin at 16-18 weeks. CONCLUSION: Twin reversed arterial perfusion carries a high mortality between the first and early second trimester.
引用
收藏
页码:213.e1 / 213.e4
页数:4
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