Antioxidant flavonoid glycosides from Daphniphyllum calycinum

被引：99
作者：
Gamez, EJC
Luyengi, L
Lee, SK
Zhu, LF
Zhou, BN
Fong, HHS
Pezzuto, JM
Kinghorn, AD [1 ]
机构：
[1] Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA
[2] Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Chicago, IL 60612 USA
[3] Acad Sinica, S China Inst Bot, Guangzhou, Peoples R China
[4] Acad Sinica, Shanghai Inst Mat Med, Shanghai, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 05期
关键词：
D O I：
10.1021/np9800203
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A novel flavonoid diglycoside, 5,6,7,4'-tetrahydroxyflavonol 3-O-rutinoside (1), and a previously known compound, kaempferol 3-O-neohesperidoside (2), were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay. The structure of 1 was elucidated by a combination of spectroscopic methods, and compounds 1 and 2 were found to be moderately active as antioxidants in the DPPH assay.
引用
收藏
页码：706 / 708
页数：3
相关论文
共 11 条
[1]  
Agrawal P. K., 1989, CARBON 13 NMR FLAVON, P95
[2]   NMR-SPECTROSCOPY IN THE STRUCTURAL ELUCIDATION OF OLIGOSACCHARIDES AND GLYCOSIDES [J].
AGRAWAL, PK .
PHYTOCHEMISTRY, 1992, 31 (10) :3307-3330
[3]  
ARTHUR H. R., 1965, PHYTOCHEMISTRY, V4, P627, DOI 10.1016/S0031-9422(00)86225-1
[4]   The flavonoids of Allium ursinum [J].
Carotenuto, A ;
DeFeo, V ;
Fattorusso, E ;
Lanzotti, V ;
Magno, S ;
Cicala, C .
PHYTOCHEMISTRY, 1996, 41 (02) :531-536
[5]   Antioxidant properties of hydroxy-flavones [J].
Cotelle, N ;
Bernier, JL ;
Catteau, JP ;
Pommery, J ;
Wallet, JC ;
Gaydou, EM .
FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (01) :35-43
[6]   8-METHOXYKAEMPFEROL 3-NEOHESPERIDOSIDE AND OTHER FLAVONOIDS FROM BEE POLLEN OF CRATAEGUS-MONOGYNA [J].
DAUGUET, JC ;
BERT, M ;
DOLLEY, J ;
BEKAERT, A ;
LEWIN, G .
PHYTOCHEMISTRY, 1993, 33 (06) :1503-1505
[7]  
GRAY DE, 1971, ASIAN J MED, V7, P409
[8]   C-13 NMR-STUDIES OF FLAVONOIDS .3. NATURALLY OCCURRING FLAVONOID GLYCOSIDES AND THEIR ACYLATED DERIVATIVES [J].
MARKHAM, KR ;
TERNAI, B ;
STANLEY, R ;
GEIGER, H ;
MABRY, TJ .
TETRAHEDRON, 1978, 34 (09) :1389-1397
[9]   Structural aspects of antioxidant activity of flavonoids [J].
vanAcker, SABE ;
vandenBerg, DJ ;
Tromp, MNJL ;
Griffioen, DH ;
VanBennekom, WP ;
VanderVijgh, WJF ;
Bast, A .
FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (03) :331-342
[10]  
Yokozawa T, 1997, PHYTOTHER RES, V11, P446, DOI 10.1002/(SICI)1099-1573(199709)11:6<446::AID-PTR128>3.3.CO
12