Efficacy and Safety of Single-Agent Quizartinib (Q), a Potent and Selective FLT3 Inhibitor (FLT3i), in Patients (pts) with FLT3-Internal Tandem Duplication (FLT3-ITD)-Mutated Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) Enrolled in the Global, Phase 3, Randomized Controlled Quantum-R Trial

被引：5

作者：

Cortes, Jorge E. ^{[1
]}

Khaled, Samer K. ^{[2
]}

Martinelli, Giovanni ^{[3
]}

Perl, Alexander E. ^{[4
]}

Ganguly, Siddhartha ^{[5
]}

Russell, Nigel H. ^{[6
]}

Kramer, Alwin ^{[7
,8
]}

Dombret, Herve ^{[9
]}

Hogge, Donna ^{[10
]}

Jonas, Brian A. ^{[11
]}

Leung, Anskar Y. -H. ^{[12
]}

Mehta, Priyanka ^{[13
]}

Montesinos, Pau ^{[14
]}

Radsak, Markus P. ^{[15
]}

Sica, Simona ^{[16
]}

Arunachalam, Meena ^{[17
]}

Holmes, Melissa ^{[17
]}

Kobayashi, Ken ^{[17
]}

Namuyinga, Ruth ^{[17
]}

Ge, Nanxiang ^{[17
]}

Yver, Antoine ^{[17
]}

Zhang, Yufen ^{[17
]}

Levis, Mark J. ^{[18
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA

[2] City Hope Natl Med Ctr, Dept Hematol HCT, Duarte, CA USA

[3] IRCCS, Ist Sci Romagnolo Studio & Cura Tumor IRST, Meldola, Italy

[4] Univ Penn, Dept Med, Div Hematol Oncol, Philadelphia, PA 19104 USA

[5] Univ Kansas, Med Ctr, Westwood, KS USA

[6] Nottingham Univ Hosp, Nottingham, England

[7] Heidelberg Univ, Med Klin 5, Klin Kooperat Einheit Mol Hamatol Onkol, Heidelberg, Germany

[8] German Canc Res Ctr, Heidelberg, Germany

[9] Univ Paris Diderot, St Louis Hosp, Paris, France

[10] Vancouver Gen Hosp, Vancouver, BC, Canada

[11] Univ Calif Davis, Comprehens Canc Ctr, Sacramento, CA 95817 USA

[12] Univ Hong Kong, Hong Kong, Peoples R China

[13] Univ Bristol, Bristol, Avon, England

[14] Hosp Univ & Politecn La Fe, Valencia, Spain

[15] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Hematol Med Oncol & Pneumol, Mainz, Germany

[16] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli IRCCS, Hematol Dept, Rome, Italy

[17] Daiichi Sankyo Inc, Basking Ridge, NJ USA

[18] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

来源：

BLOOD | 2018年 / 132卷

关键词：

D O I：

10.1182/blood-2018-99-110439

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

563

引用

页数：5