Recent Progress in Fluorescent Probes for Diabetes Visualization and Drug Therapy

被引：15
作者：
Jia, Tong-Tong [1 ]
Li, Yashan [2 ]
Niu, Huawei [3 ]
机构：
[1] Luoyang Normal Univ, Coll Chem & Chem Engn, Luoyang 471934, Peoples R China
[2] Chuxiong Normal Univ, Coll Resources Environm & Chem, Chuxiong 675000, Peoples R China
[3] Henan Univ Sci & Technol, Coll Food & Bioengn, Luoyang 471000, Peoples R China
来源：
CHEMOSENSORS | 2022年 / 10卷 / 07期
关键词：
fluorescence; probe; diabetes; complications; biomarker; visualization; treatment; ENDOPLASMIC-RETICULUM; SUPEROXIDE ANION; OXIDATIVE STRESS; LIPID DROPLETS; CELL POLARITY; DPP-IV; PEROXYNITRITE; INSULIN; TIME; PH;
D O I：
10.3390/chemosensors10070280
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Diabetes has become one of the most prevalent endocrine and metabolic diseases that threaten human health, and it is accompanied by serious complications. Therefore, it is vital and pressing to develop novel strategies or tools for prewarning and therapy of diabetes and its complications. Fluorescent probes have been widely applied in the detection of diabetes due to the fact of their attractive advantages. In this report, we comprehensively summarize the recent progress and development of fluorescent probes in detecting the changes in the various biomolecules in diabetes and its complications. We also discuss the design of fluorescent probes for monitoring diabetes in detail. We expect this review will provide new ideas for the development of fluorescent probes suitable for the prewarning and therapy of diabetes in future clinical transformation and application.
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页数：30
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