Chemohormonal Therapy for Hormone-Sensitive Prostate Cancer: A Review

被引：2
|
作者：
Kyriakopoulos, Christos E. [1 ]
Liu, Glenn [1 ]
机构：
[1] Univ Wisconsin, Carbone Canc Ctr, 600 Highland Ave, Madison, WI 53792 USA
来源：
CANCER JOURNAL | 2016年 / 22卷 / 05期
关键词：
Chemohormonal; Docetaxel; Hormone-sensitive; Prostate cancer; ANDROGEN-DEPRIVATION THERAPY; DOCETAXEL; SURVIVAL; MITOXANTRONE; PREDNISONE; FLUTAMIDE; MEN;
D O I：
10.1097/PPO.0000000000000215
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Ever since the critical role of androgen deprivation therapy for the treatment of metastatic prostate cancer was established, several trials aimed to show an improved outcome with the early introduction of chemotherapy in metastatic disease. Until recently, all these trialsincluding the GETUG-AFU 15 trialfailed to confirm an improvement in survival. The recently published CHAARTED and STAMPEDE trials showed a striking benefit and changed the standard of care for patients with newly diagnosed metastatic prostate cancer. We summarize the evidence that emerged from these trials that support the use of combined chemohormonal therapy in metastatic hormone-sensitive prostate cancer.
引用
收藏
页码：322 / 325
页数：4
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