Monocyte count-to-high-density lipoprotein-cholesterol ratio is associated with abdominal aortic aneurysm size

被引:21
作者
Cagli, Kumral [1 ]
Tok, Derya [1 ]
Turak, Osman [1 ]
Gunertem, Eren [2 ]
Yayla, Cagri [1 ]
Lafci, Gokhan [2 ]
Ulas, Mahmut Mustafa [2 ]
Cagli, Kerim [2 ]
机构
[1] Turkiye Yuksek Ihtisas Training & Res Hosp, Dept Cardiol, Ankara, Turkey
[2] Turkiye Yuksek Ihtisas Training & Res Hosp, Dept Cardiovasc Surg, Ankara, Turkey
关键词
abdominal aortic aneurysm; coronary artery disease; C-reactive protein; hypertension; monocyte/high-density lipoprotein cholesterol ratio; CHRONIC KIDNEY-DISEASE; RISK-FACTORS; INFLAMMATORY RESPONSE; PROGRESSION; HDL; PATHOGENESIS; MORTALITY; ELEVATION; COHORT; WALL;
D O I
10.2217/bmm-2016-0157
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Aim: To determine the association of monocyte count-to-high-density lipoprotein (HDL)-cholesterol ratio, a recently emerged inflammatory marker, with abdominal aortic aneurysm (AAA) size. Patients & methods: A total of 120 asymptomatic AAA subjects (99 male, mean age: 67.1 +/- 10.2 years) were enrolled into the study. All data were compared between patients with low and high admission monocyte/HDL ratio. Multivariate linear regression analysis was performed to study the relationship between different variables and AAA size. Results: Compared to patients with below-median monocyte/HDL ratio, aneurysm diameter was significantly higher in above-median monocyte/HDL ratio group (54.3 +/- 10.6 mm vs 62.0 +/- 12.4 mm, p < 0.001, respectively). Hypertension, coronary artery disease, monocyte/HDL ratio and C-reactive protein were independently associated with AAA diameter. Conclusion: Monocyte/HDL ratio is independently associated with AAA size.
引用
收藏
页码:1039 / 1047
页数:9
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