Monocyte count-to-high-density lipoprotein-cholesterol ratio is associated with abdominal aortic aneurysm size

被引：21

作者：

Cagli, Kumral ^{[1
]}

Tok, Derya ^{[1
]}

Turak, Osman ^{[1
]}

Gunertem, Eren ^{[2
]}

Yayla, Cagri ^{[1
]}

Lafci, Gokhan ^{[2
]}

Ulas, Mahmut Mustafa ^{[2
]}

Cagli, Kerim ^{[2
]}

机构：

[1] Turkiye Yuksek Ihtisas Training & Res Hosp, Dept Cardiol, Ankara, Turkey

[2] Turkiye Yuksek Ihtisas Training & Res Hosp, Dept Cardiovasc Surg, Ankara, Turkey

来源：

BIOMARKERS IN MEDICINE | 2016年 / 10卷 / 10期

关键词：

abdominal aortic aneurysm; coronary artery disease; C-reactive protein; hypertension; monocyte/high-density lipoprotein cholesterol ratio; CHRONIC KIDNEY-DISEASE; RISK-FACTORS; INFLAMMATORY RESPONSE; PROGRESSION; HDL; PATHOGENESIS; MORTALITY; ELEVATION; COHORT; WALL;

D O I：

10.2217/bmm-2016-0157

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Aim: To determine the association of monocyte count-to-high-density lipoprotein (HDL)-cholesterol ratio, a recently emerged inflammatory marker, with abdominal aortic aneurysm (AAA) size. Patients & methods: A total of 120 asymptomatic AAA subjects (99 male, mean age: 67.1 +/- 10.2 years) were enrolled into the study. All data were compared between patients with low and high admission monocyte/HDL ratio. Multivariate linear regression analysis was performed to study the relationship between different variables and AAA size. Results: Compared to patients with below-median monocyte/HDL ratio, aneurysm diameter was significantly higher in above-median monocyte/HDL ratio group (54.3 +/- 10.6 mm vs 62.0 +/- 12.4 mm, p < 0.001, respectively). Hypertension, coronary artery disease, monocyte/HDL ratio and C-reactive protein were independently associated with AAA diameter. Conclusion: Monocyte/HDL ratio is independently associated with AAA size.

引用

页码：1039 / 1047

页数：9

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