Mechanism of the interaction between benthiavalicarb-isopropyl and human serum albumin

被引：13
|
作者：
Zhang, Jian [1 ]
Wang, Zishi [1 ]
Xing, Yue [1 ]
Hou, Chenxin [1 ]
Zhou, Qin [1 ]
Sun, Yan [1 ]
Sun, Yuan [1 ]
Xu, Hongliang [1 ,2 ]
Gao, Jinsheng [1 ,2 ]
机构：
[1] Heilongjiang Univ, Sch Agr Resources & Environm, Harbin 150080, Peoples R China
[2] Heilongjiang Univ, Pesticide Engn Ctr, Harbin, Peoples R China
来源：
SPECTROSCOPY LETTERS | 2020年 / 53卷 / 05期
基金：
中国博士后科学基金;
关键词：
Benthiavalicarb-isopropyl; mechanism; molecular docking; human serum albumin; spectroscopic studies; MOLECULAR DOCKING; CRYSTAL-STRUCTURE; IN-VITRO; BINDING; SPECTROSCOPY; HSA; HYDROCHLORIDE; COMPLEX; MILK; DRUG;
D O I：
10.1080/00387010.2020.1756343
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
The interaction between benthiavalicarb-isopropyl and human serum albumin was studied by ultraviolet-visible absorption, fluorescence, synchronous fluorescence, three-dimensional fluorescence, circular dichroism spectroscopies and molecular docking. The results revealed that the effect of benthiavalicarb-isopropyl on human serum albumin was static quenching. The number of binding sites, binding constants, and binding distance were obtained. The interaction of benthiavalicarb-isopropyl to human serum albumin was mainly through hydrogen bond and van der Waals force. The conformation of human serum albumin changed slightly. The interaction details were studied by molecular docking method. This study elucidated the mechanism of the interaction between benthiavalicarb-isopropyl and human serum albumin.
引用
收藏
页码：360 / 371
页数：12
相关论文
共 50 条
  • [1] Development of a new fungicide, benthiavalicarb-isopropyl
    Sakai, Junetsu
    Miura, Ichiro
    Shibata, Masaru
    Yonekura, Norihisa
    Hiyoshi, Hidetaka
    Takagaki, Makiichi
    Nagayama, Kozo
    JOURNAL OF PESTICIDE SCIENCE, 2010, 35 (04) : 488 - 489
  • [2] Degradation of the fungicide benthiavalicarb-isopropyl in soils
    Ikeda, M
    Usami, S
    Mizutani, H
    Yagi, A
    JOURNAL OF PESTICIDE SCIENCE, 2005, 30 (01) : 22 - 30
  • [3] 杀菌剂benthiavalicarb-isopropyl的开发
    张一宾
    世界农药, 2004, (06) : 4 - 8+26
  • [4] Peer review of the pesticide risk assessment of the active substance benthiavalicarb (variant assessed benthiavalicarb-isopropyl)
    Alvarez, Fernando
    Arena, Maria
    Auteri, Domenica
    Borroto, Jorge
    Brancato, Alba
    Cabrera, Luis Carrasco
    Castoldi, Anna Federica
    Chiusolo, Arianna
    Colagiorgi, Angelo
    Colas, Mathilde
    Crivellente, Federica
    De Lentdecker, Chloe
    Egsmose, Mark
    Fait, Gabriella
    Ferilli, Franco
    Gouliarmou, Varvara
    Greco, Luna
    Ippolito, Alessio
    Istace, Frederique
    Jarrah, Samira
    Kardassi, Dimitra
    Kienzler, Aude
    Leuschner, Renata
    Lava, Roberto
    Linguadoca, Alberto
    Lythgo, Christopher
    Magrans, Oriol
    Mangas, Iris
    Miron, Ileana
    Molnar, Tunde
    Padovani, Laura
    Morte, Juan Manuel Parra
    Pedersen, Ragnor
    Reich, Hermine
    Santos, Miguel
    Sharp, Rachel
    Szentes, Csaba
    Terron, Andrea
    Tiramani, Manuela
    Vagenende, Benedicte
    Villamar-Bouza, Laura
    EFSA JOURNAL, 2021, 19 (09)
  • [5] Effects of a novel fungicide benthiavalicarb-isopropyl against oomycete fungal diseases
    Miyake, Y
    Sakai, J
    Miura, I
    Nagayama, K
    Shibata, M
    BCPC INTERNATIONAL CONGRESS CROP SCIENCE & TECHNOLOGY 2003, VOL 1 AND 2, CONGRESS PROCEEDINGS, 2003, : 105 - 112
  • [6] New fungicide benthiavalicarb-isopropyl plus mancozeb for foliar use in potatoes in Europe
    Hofman, TW
    Boon, SM
    Coster, G
    van Oudheusden, Z
    Ploss, H
    Nagayama, K
    BCPC INTERNATIONAL CONGRESS CROP SCIENCE & TECHNOLOGY 2003, VOL 1 AND 2, CONGRESS PROCEEDINGS, 2003, : 413 - 418
  • [7] 新颖杀菌剂苯噻菌胺(benthiavalicarb-isopropyl)
    冯化成
    世界农药, 2008, 30 (03) : 51 - 51
  • [8] Molecular Mechanism on the Interaction between Alisols and Human Serum Albumin
    Xu Fei
    Zhang Linqun
    He Liwei
    Gu Wei
    Fang Fang
    Wu Qinan
    Zhao Bo
    ACTA CHIMICA SINICA, 2011, 69 (19) : 2228 - 2234
  • [9] Residue analysis of the fungicide benthiavalicarb-isopropyl and its degradation products in upland field soil
    Mizutani, H
    Suzuki, J
    Saito, Y
    Ikeda, M
    Yagi, A
    JOURNAL OF PESTICIDE SCIENCE, 2004, 29 (02) : 87 - 95
  • [10] Mechanism of Interaction between Chrysin and Different Configurations of Human Serum Albumin
    Liu Yuan
    Long Mei
    Xie Meng-Xia
    ACTA PHYSICO-CHIMICA SINICA, 2013, 29 (12) : 2647 - 2654
12345