Multiple Solitary Plasmacytomas With Multifocal Bone Involvement Diagnosed With 68Ga-Prostate-Specific Membrane Antigen PET/CT

被引：7

作者：

Alabed, Yazan Z. ^{[1
]}

机构：

[1] Gulf Int Canc Ctr, Dept Nucl Med, PET CT Unit, POB 5882, Abu Dhabi, U Arab Emirates

来源：

CLINICAL NUCLEAR MEDICINE | 2020年 / 45卷 / 01期

关键词：

Ga-68; myeloma; PET/CT; plasmacytoma; SMA; POSITRON-EMISSION-TOMOGRAPHY; LYMPH-NODE METASTASIS; PROSTATE-CANCER;

D O I：

10.1097/RLU.0000000000002682

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 63-year-old man with elevated prostate-specific antigen serum levels and enlarged prostate gland underwent ultrasound-guided transrectal biopsy, which did not reveal any evidence of malignancy. In order to help guidance of repeat biopsy, Ga-68-prostate-specific membrane antigentargeted ligand PET (PSMA PET/CT) was ordered. PET/CT scan showed no abnormal PSMA expression within the prostate gland. There were, however, multiple PSMA-expressing osteolytic lesions throughout the axial skeleton. Bone lesion biopsy obtained for final workup revealed multiple solitary plasmacytomas with multifocal bone involvement. This rare case highlights the utility of PSMA PET/CT in diagnosing nonprostate malignancies.

引用

页码：E51 / E52

页数：2

共 15 条

[1] 68Ga-labeled Prostate-specific Membrane Antigen Positron Emission Tomography for Prostate Cancer Imaging: The New Kid on the Block-Early or Too Early to Draw Conclusions?
Eiber, Matthias
Herrmann, Ken
Fendler, Wolfgang P.
Maurer, Tobias
[J]. EUROPEAN UROLOGY, 2016, 70 (06) : 938 - 940
[2] Prostate cancer-specific PET radiotracers: A review on the clinical utility in recurrent disease
Evans, Jaden D.
Jethwa, Krishan R.
Ost, Piet
Williams, Scott
Kwon, Eugene D.
Lowe, Val J.
Davis, Brian J.
[J]. PRACTICAL RADIATION ONCOLOGY, 2018, 8 (01) : 28 - 39
[3] Imaging of Nonprostate Cancers Using PSMA-Targeted Radiotracers: Rationale, Current State of the Field, and a Call to Arms
Fragomeni, Roberto A. Salas
Amir, Tali
Sheikhbahaei, Sara
Harvey, Susan C.
Javadi, Mehrbod S.
Solnesl, Lilja B.
Kiess, Ana P.
Allaf, Mohamad E.
Pomper, Martin G.
Gorin, Michael A.
Rowel, Steven P.
[J]. JOURNAL OF NUCLEAR MEDICINE, 2018, 59 (06) : 871 - 877
[4] Froehner Michael, 2017, Case Rep Urol, V2017, P1654231, DOI 10.1155/2017/1654231
[5] Splenunculus Masquerading as Prostate-specific Membrane Antigen-positive Lymph Node Metastasis in a Patient With Prostate-specific Antigen Relapse After Radical Prostatectomy
Froehner, Michael
Zoephel, Klaus
Hoelscher, Tobias
Laniado, Michael
Wirth, Manfred P.
[J]. UROLOGY, 2016, 94 : E1 - E2
[6] 68Ga-PSMA Positron Emission Tomography/Computed Tomography Provides Accurate Staging of Lymph Node Regions Prior to Lymph Node Dissection in Patients with Prostate Cancer
Herlemann, Annika
Wenter, Vera
Kretschmer, Alexander
Thierfelder, Kolja M.
Bartenstein, Peter
Faber, Claudius
Gildehaus, Franz-Josef
Stief, Christian G.
Gratzke, Christian
Fendler, Wolfgang P.
[J]. EUROPEAN UROLOGY, 2016, 70 (04) : 553 - 557
[7] Prostate-Specific Membrane Antigen PET/CT: False-Positive Results due to Sarcoidosis?
Hermann, Robert M.
Djannatian, Manoutschehr
Czech, Norbert
Nitsche, Mirko
[J]. CASE REPORTS IN ONCOLOGY, 2016, 9 (02): : 457 - 463
[8] Skeletal Plasmacytoma: Progression of disease and impact of local treatment; an analysis of SEER database
Jawad, Muhammad Umar
Scully, Sean P.
[J]. JOURNAL OF HEMATOLOGY & ONCOLOGY, 2009, 2
[9] A Review for Solitary Plasmacytoma of Bone and Extramedullary Plasmacytoma
Kilciksiz, Sevil
Karakoyun-Celik, Omur
Agaoglu, Fulya Yaman
Haydaroglu, Ayfer
[J]. SCIENTIFIC WORLD JOURNAL, 2012,
[10] [68Ga]PSMA-HBED uptake mimicking lymph node metastasis in coeliac ganglia: an important pitfall in clinical practice
Krohn, Thomas
Verburg, Frederik A.
Pufe, Thomas
Neuhuber, Winfried
Vogg, Andreas
Heinzel, Alexander
Mottaghy, Felix M.
Behrendt, Florian F.
[J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 (02) : 210 - 214

← 1 2 →