Isogosterones A-D, antifouling 13,17-Secosteroids from an octocoral Dendronephthya sp.

被引：47
作者：
Tomono, Y
Hirota, H
Fusetani, N [1 ]
机构：
[1] Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan
[2] Res Dev Corp Japan, Fusetani Biofouling Project, Exploratory Res Adv Technol, Isogo Ku, Yokohama, Kanagawa 2350017, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 07期
关键词：
D O I：
10.1021/jo981828v
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Four antifouling secosteroids named isogosterones A-D (1-4) have been isolated from a Japanese octocoral Dendronephthya sp. Their structures were elucidated on the basis of spectroscopic data as 12 alpha-acetoxy-13,17-seco-cholesta-1,4-dien-3-ones possessing a hemiacetal or acetal functionality. Isogosterones inhibited larval settlement of the barnacle Balanus amphitrite with an EC50 value of 2.2 mu g/mL.
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收藏
页码：2272 / 2275
页数：4
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