P/S ligands derived from carbohydrates in Rh-catalyzed hydrosilylation of ketones

被引：11

作者：

Khiar, Noureddine ^{[1
]}

Pernia Leal, Manuel ^{[1
]}

Navas, Raquel ^{[1
]}

Francisco Moya, Juan ^{[1
]}

Garcia Perez, Maria Victoria ^{[2
]}

Fernandez, Inmaculada ^{[2
]}

机构：

[1] Univ Seville, CSIC, IIQ, Seville 41092, Spain

[2] Univ Seville, Fac Farm, Dept Quim Organ & Farmaceut, E-41012 Seville, Spain

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 02期

关键词：

ASYMMETRIC HYDROSILYLATION; ENANTIOSELECTIVE CATALYSIS; SULFINYL CHLORIDES; PHOSPHORUS LIGANDS; CARBONYL-COMPOUNDS; HYDROGENATION; COMPLEXES; RHODIUM; THIOGLYCOSIDES; TEMPERATURE;

D O I：

10.1039/c1ob06305g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reported is the synthesis of a number of diastereomerically pure cationic Rh(I)-complexes I starting from phosphinite thioglycosides. These complexes were used in the asymmetric hydrosilylation of prochiral ketones. The reactivity and enantioselectivity of the reaction was shown to be dependent on the pyranose ring, the substituent at the sulfur atom, the hydroxylic protective groups and most significantly on the alkene co-ligand.

引用

页码：355 / 360

页数：6

共 54 条

[1] THE STEREODYNAMICS OF METAL-COMPLEXES OF SULFUR-CONTAINING, SELENIUM-CONTAINING, AND TELLURIUM-CONTAINING LIGANDS [J].