Facile Access to Far-Red Fluorescent Probes with Through-Space Charge-Transfer Effects for In Vivo Two-Photon Microscopy of the Mouse Cerebrovascular System

被引:24
作者
Hong, Yingjuan [1 ]
Geng, Weihang [2 ]
Zhang, Tian [4 ]
Gong, Guangshuai [4 ]
Li, Chongyang [1 ]
Zheng, Canze [1 ]
Liu, Feng [1 ]
Qian, Jun [2 ]
Chen, Ming [1 ]
Tang, Ben Zhong [3 ]
机构
[1] Jinan Univ, Coll Chem & Mat Sci, Guangzhou 510632, Peoples R China
[2] Zhejiang Univ, State Key Lab Modern Opt Instrumentat, Ctr Opt & Electromagnet Res, Coll Opt Sci & Engn,Int Res Ctr Adv Photon, Hangzhou 310058, Peoples R China
[3] Chinese Univ Hong Kong, Sch Sci & Engn, Shenzhen Inst Aggregate Sci & Technol, Shenzhen 518172, Guangdong, Peoples R China
[4] Shandong Univ Technol, Sch Chem & Chem Engn, Zibo 255049, Peoples R China
基金
中国国家自然科学基金;
关键词
Bioimaging; Fluorescent Probes; Through-Space Charge Transfer; Twist-Plus-Twist Interaction; Two-Photon Excitation; AGGREGATION-INDUCED EMISSION; ACTIVATED DELAYED FLUORESCENCE; TRANSFER COMPLEXES; FIELD; SPECTROSCOPY; ASSEMBLIES; TRANSPORT; PERYLENE; PRESSURE; PROTEIN;
D O I
10.1002/anie.202209590
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Much effort has been devoted to the generation of fluorescent probes by synthetic approaches. In this study, we developed a facile strategy to construct far-red fluorescent probes based on through-space charge transfer within complexes of acceptors and donors and their "twist+twist" interactions. Owing to their rare two-photon excitation property, the complexes could be used for in vivo imaging of the mouse cerebrovascular system.
引用
收藏
页数:6
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