Structural/functional homology between the bacterial and eukaryotic cytoskeletons

被引:55
作者
Amos, LA [1 ]
van den Ent, F [1 ]
Löwe, J [1 ]
机构
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
关键词
D O I
10.1016/j.ceb.2003.11.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Structural proteins are now known to be as necessary for controlling cell division and cell shape in prokaryotes as they are in eukaryotes. Bacterial ParM and MreB not only have atomic structures that resemble eukaryotic actin and form similar filaments, but they are also equivalent in function: the assembly of ParM drives intracellular motility and MreB maintains the shape of the cell. FtsZ resembles tubulin in structure and in its dynamic assembly, and is similarly controlled by accessory proteins. Bacterial MinD and eukaryotic dynamin appear to have similar functions in membrane control. In dividing eukaryotic organelles of bacterial origin, bacterial and eukaryotic proteins work together.
引用
收藏
页码:24 / 31
页数:8
相关论文
共 67 条
[1]   Assembly of cell division proteins at the E-coli cell center [J].
Buddelmeijer, N ;
Beckwith, J .
CURRENT OPINION IN MICROBIOLOGY, 2002, 5 (06) :553-557
[2]   Apparent cooperative assembly of the bacterial cell division protein FtsZ demonstrated by isothermal titration calorimetry [J].
Caplan, MR ;
Erickson, HP .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (16) :13784-13788
[3]   The bacterial cytoskeleton:: In vivo dynamics of the actin-like protein Mbl of Bacillus subtilis [J].
Carballido-López, R ;
Errington, J .
DEVELOPMENTAL CELL, 2003, 4 (01) :19-28
[4]   Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ [J].
Cordell, SC ;
Robinson, EJH ;
Löwe, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (13) :7889-7894
[5]   Crystal structure of the bacterial cell division inhibitor MinC [J].
Cordell, SC ;
Anderson, RE ;
Löwe, J .
EMBO JOURNAL, 2001, 20 (10) :2454-2461
[6]   Crystal structure of the bacterial cell division regulator MinD [J].
Cordell, SC ;
Löwe, J .
FEBS LETTERS, 2001, 492 (1-2) :160-+
[7]   Control of cell morphogenesis in bacteria: Two distinct ways to make a rod-shaped cell [J].
Daniel, RA ;
Errington, J .
CELL, 2003, 113 (06) :767-776
[8]   Alteration of microtubule dynamic instability during preprophase band formation revealed by yellow fluorescent protein-CLIP170 microtubule plus-end labeling [J].
Dhonukshe, P ;
Gadella, TWJ .
PLANT CELL, 2003, 15 (03) :597-611
[9]   Clamped-filament elongation model for actin-based motors [J].
Dickinson, RB ;
Purich, DL .
BIOPHYSICAL JOURNAL, 2002, 82 (02) :605-617
[10]   Actin's prokaryotic homologs [J].
Egelman, EH .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2003, 13 (02) :244-248