Taste function in patients with Parkinson disease

被引:32
作者
Kim, Han-Joon [1 ,2 ]
Jeon, Beom S. [1 ,2 ]
Lee, Jee-Young [2 ,3 ]
Cho, Yong-Jin [4 ,5 ]
Hong, Keun-Sik [4 ,5 ]
Cho, Joong-Yang [4 ,5 ]
机构
[1] Seoul Natl Univ Hosp, Coll Med, Dept Neurol, Movement Disorder Ctr,Neurosci Res Inst, Seoul 110744, South Korea
[2] Seoul Natl Univ Hosp, Parkinson Dis Study Grp, Clin Res Inst, Seoul 110744, South Korea
[3] Seoul Natl Univ, Coll Med, Dept Neurol, Metropolitan Boramae Hosp, Seoul, South Korea
[4] Inje Univ Ilsan Paik Hosp, Dept Neurol, Goyang Si, Gyeonggi Do, South Korea
[5] Inje Univ Ilsan Paik Hosp, Clin Res Ctr, Goyang Si, Gyeonggi Do, South Korea
关键词
Parkinson disease; Taste; Smell; Nonmotor symptoms; SMELL; DISORDERS;
D O I
10.1007/s00415-010-5884-x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Despite the important role of taste function in nutrition and health, little is known about changes in taste function caused by Parkinson disease (PD). The taste function of 31 PD patients and 29 healthy controls was assessed quantitatively using filter paper taste strip tests (TSTs) impregnated with four basic taste qualities at four different concentrations. The mean TST score was significantly lower in PD patients, as a consequence of taste impairment in the female PD patients (it did not differ significantly in males), which was likely to be attributable to the lower Mini-Mental State Examination score in patients with PD than in controls in women. TST scores in PD patients were not correlated with patient age, duration, or severity of their PD, or olfactory function. The findings of our study suggest that taste dysfunction should be included in the list of nonmotor symptoms of PD.
引用
收藏
页码:1076 / 1079
页数:4
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